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弱电鱼(裸背电鳗科)尾侧小脑和电感觉侧线叶中氨基酸的层状分布。

The laminar distribution of amino acids in the caudal cerebellum and electrosensory lateral line lobe of weakly electric fish (Gymnotidae).

作者信息

Nadi S, Maler L

机构信息

NINCDS, Bethesda, MD 20892.

出版信息

Brain Res. 1987 Nov 10;425(2):218-24. doi: 10.1016/0006-8993(87)90504-x.

DOI:10.1016/0006-8993(87)90504-x
PMID:2892571
Abstract

We have studied the distribution of the putative amino acid neurotransmitters glutamate, aspartate, gamma-aminobutyric acid (GABA), glycine, taurine and beta-alanine in the caudal cerebellar lobe and electrosensory lateral line lobe (ELL) of weakly electric gymnotid fish. In the caudal lobe of the cerebellum, the levels of the various amino acids in the granular and molecular layers are comparable to the levels in the rat cerebellum, with the exception of taurine which is present in greater amounts in the gymnotid. In the ELL, these amino acids are differentially distributed in the various layers of this structure. Glutamate and taurine are enriched in the molecular layer, whereas GABA, aspartate, and beta-alanine are enriched in the deep neuropil + granular layers. Glycine is slightly enriched in the pyramidal cell layer.

摘要

我们研究了弱电裸背电鳗目鱼类尾侧小脑叶和电感觉侧线叶(ELL)中假定的氨基酸神经递质谷氨酸、天冬氨酸、γ-氨基丁酸(GABA)、甘氨酸、牛磺酸和β-丙氨酸的分布情况。在小脑尾叶中,颗粒层和分子层中各种氨基酸的水平与大鼠小脑中的水平相当,但牛磺酸除外,牛磺酸在裸背电鳗目鱼类中的含量更高。在ELL中,这些氨基酸在该结构的不同层中呈差异分布。谷氨酸和牛磺酸在分子层中富集,而GABA、天冬氨酸和β-丙氨酸在深部神经纤维网+颗粒层中富集。甘氨酸在锥体细胞层中略有富集。

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引用本文的文献

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The role of amino acid neurotransmitters in the descending control of electroreception.
J Comp Physiol A. 1993 May;172(4):409-23. doi: 10.1007/BF00213523.
2
Morphological and electrophysiological properties of a novel in vitro preparation: the electrosensory lateral line lobe brain slice.一种新型体外制备物的形态学和电生理特性:电感觉侧线叶脑片。
J Comp Physiol A. 1988 Aug;163(4):489-506. doi: 10.1007/BF00604903.
3
GABAergic inhibition shapes temporal and spatial response properties of pyramidal cells in the electrosensory lateral line lobe of gymnotiform fish.γ-氨基丁酸能抑制作用塑造了裸背电鳗目鱼类电感受侧线叶中锥体细胞的时间和空间反应特性。
J Comp Physiol A. 1989 Jan;164(3):391-407. doi: 10.1007/BF00612998.
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Morphological correlates of pyramidal cell adaptation rate in the electrosensory lateral line lobe of weakly electric fish.弱电鱼电感觉侧线叶中锥体细胞适应率的形态学关联
J Comp Physiol A. 1991 Apr;168(4):393-407. doi: 10.1007/BF00199600.