Dax E M
Laboratory of Neuroendocrine Immunology, National Institute on Aging, Baltimore, Maryland.
Endocrinol Metab Clin North Am. 1987 Dec;16(4):947-63.
The relevance of membrane receptor systems to aging in animals has been studied extensively. A large number of hormones, drugs, and transmitters convey their signals via membrane receptors. Many physiologic and biochemical processes are mediated via membrane receptors. Therefore, exploration of the age-related changes in the interactions of receptors with coupling proteins second-messenger systems and their surrounding environments are of obvious significance.