biospear：用于惩罚 Cox 回归中生物标志物选择的 R 包。
biospear: an R package for biomarker selection in penalized Cox regression.
机构信息
Gustave Roussy, Université Paris-Saclay, Service de biostatistique et d'épidémiologie, Villejuif, F-94805, France.
Université Paris-Saclay, Univ. Paris-Sud, UVSQ, CESP, INSERM, Villejuif, F-94805, France.
出版信息
Bioinformatics. 2018 Jan 1;34(1):112-113. doi: 10.1093/bioinformatics/btx560.
SUMMARY
The R package biospear allows selecting the biomarkers with the strongest impact on survival and on the treatment effect in high-dimensional Cox models, and estimating expected survival probabilities. Most of the implemented approaches are based on penalized regression techniques.
AVAILABILITY AND IMPLEMENTATION
The package is available on the CRAN. (https://CRAN.R-project.org/package=biospear).
CONTACT
stefan.michiels@gustaveroussy.fr.
SUPPLEMENTARY INFORMATION
Supplementary data are available at Bioinformatics online.
摘要
R 包 biospear 允许在高维 Cox 模型中选择对生存和治疗效果影响最强的生物标志物，并估计预期生存概率。大多数实现的方法都基于惩罚回归技术。
可用性和实现
该包可在 CRAN 上获得。（https://CRAN.R-project.org/package=biospear）。
联系人
stefan.michiels@gustaveroussy.fr。
补充信息
补充数据可在生物信息学在线获得。
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