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周末入院对烧伤患者死亡率及其他结局的影响:一项全国性分析。

Impact of weekend admission on mortality and other outcomes among patients with burn injury: A nationwide analysis.

作者信息

Peluso Heather, Abougergi Marwan S, Caffrey Julie

机构信息

Department of Surgery, University of South Carolina, Greenville Health System, 701 Grove Road, Greenville, SC 29605, United States.

Catalyst Medical Consulting, 722 Elmbrook Drive, Simpsonville, SC 29681, United States.

出版信息

Burns. 2017 Dec;43(8):1654-1661. doi: 10.1016/j.burns.2017.08.005. Epub 2017 Sep 18.

Abstract

OBJECTIVE

To study the relationship between day of admission and important outcomes among patients with burn injuries.

METHODS

The 2014 National Inpatient Sample database was used. Inclusion criterion was a principal diagnosis of burn injury. Exclusion criteria were age <18years, superficial burn, and non-urgent admission. The primary outcome was in-hospital mortality. Secondary outcomes were morbidity (septic shock and prolonged mechanical ventilation), treatment metrics (time to surgery and parenteral or enteral nutrition (P/E-nutrition)) and resource utilization (length of stay (LOS) and total hospitalization charges and costs). Confounders were adjusted for using multivariate regression analysis.

RESULTS

A total of 21,665 patients were included, 29% of whom were admitted on weekends. Weekend admission was an independent predictor of mortality only among patients >65years old (adjusted odds ratio (aOR): 2.66 (1.13-4.51), p=0.02). Although rates of septic shock were similar for both groups (aOR): 1.25 (0.74-2.09, p=0.40), weekends were associated with higher odds of prolonged mechanical ventilation (aOR: 1.28 (1.06-1.55), p=0.01). Time to surgery (adjusted mean difference (amDiff): 0.91 (-0.07 to 1.88) days, p=0.07) and time to P/E-nutrition (amDiff: 0.40 (-3.51 to 4.30) days, p=0.80) were similar for both groups. Finally, LOS was longer for weekend admission (amDiff: 1.36 (0.09-2.63) days, p=0.04), but total charges and costs were similar for both groups (amDiff: $16,268 ($-5093-$37,629), p=0.13 and $3275 ($-2337-$8888), p=0.25).

CONCLUSIONS

Weekend admission is associated with increased mortality among patients with burn injury >65years old. Weekend admission is also associated with increased morbidity and prolonged length of stay.

摘要

目的

研究烧伤患者的入院日期与重要预后之间的关系。

方法

使用2014年全国住院患者样本数据库。纳入标准为主要诊断为烧伤。排除标准为年龄<18岁、浅表烧伤和非紧急入院。主要结局是院内死亡率。次要结局是发病率(感染性休克和长时间机械通气)、治疗指标(手术时间和肠外或肠内营养(P/E营养)时间)以及资源利用(住院时间(LOS)、总住院费用和成本)。使用多变量回归分析对混杂因素进行校正。

结果

共纳入21,665例患者,其中29%在周末入院。周末入院仅在65岁以上患者中是死亡率的独立预测因素(校正优势比(aOR):2.66(1.13 - 4.51),p = 0.02)。尽管两组感染性休克发生率相似(aOR:1.25(0.74 - 2.09),p = 0.40),但周末与长时间机械通气的较高几率相关(aOR:1.28(1.06 - 1.55),p = 0.01)。两组的手术时间(校正平均差(amDiff):0.91(-0.07至1.88)天,p = 0.07)和P/E营养时间(amDiff:0.40(-3.51至4.30)天,p = 0.80)相似。最后,周末入院的住院时间更长(amDiff:1.36(0.09 - 2.63)天,p = 0.04),但两组的总费用和成本相似(amDiff:16,268美元(-5093美元至37,629美元),p = 0.13和3275美元(-2337美元至8888美元),p = 0.25)。

结论

65岁以上烧伤患者周末入院与死亡率增加相关。周末入院还与发病率增加和住院时间延长相关。

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