抗瘙痒病相关纤维蛋白抗血清与微小螺旋体纤维蛋白发生交叉反应。
Antiserum to scrapie-associated fibril protein cross-reacts with Spiroplasma mirum fibril proteins.
作者信息
Bastian F O, Jennings R A, Gardner W A
机构信息
Department of Pathology, College of Medicine, University of South Alabama, Mobile 36617.
出版信息
J Clin Microbiol. 1987 Dec;25(12):2430-1. doi: 10.1128/jcm.25.12.2430-2431.1987.
Abstract
Protease-resistant fibril proteins purified from Spiroplasma mirum and from Creutzfeldt-Jakob disease-infected brain tissues reacted with antisera to scrapie-associated fibrils on Western immunoblot analysis. These data suggest that there are conformational similarities among spiroplasma proteins and infection-specific proteins of the transmissible spongiform encephalopathies.
摘要
从微小螺旋体和克雅氏病感染的脑组织中纯化出的抗蛋白酶原纤维蛋白，在蛋白质免疫印迹分析中与抗瘙痒病相关纤维蛋白的抗血清发生反应。这些数据表明，螺旋体蛋白与传染性海绵状脑病的感染特异性蛋白之间存在构象相似性。
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