一名儿科患者先患急性淋巴细胞白血病，后又患急性粒细胞白血病。

Acute lymphoblastic leukemia followed by acute granulocytic leukemia in a pediatric patient.

作者信息

Spector G, Youness E, Culbert S J

出版信息

Am J Clin Pathol. 1979 Aug;72(2):242-5. doi: 10.1093/ajcp/72.2.242.

DOI:10.1093/ajcp/72.2.242

Abstract

A 14-year-old white male patient had acute lymphoblastic leukemia characterized by a periodic acid-Schiff (PAS)-positive reaction, negative T and B cell markers, and negative nonspecific esterase and peroxidase reactions. Ten months after the initial diagnosis, the bone marrow appearance was compatible with acute granulocytic leukemia, with the presence of Auer rods, and with peroxidase-positive, nonspecific esterase-negative, and negative PAS reactions. Karyotyping and banding were not performed. The concurrence of both diseases in this patient is unique in pediatric oncology.

摘要

一名14岁白人男性患者患有急性淋巴细胞白血病，其特征为过碘酸希夫（PAS）阳性反应、T和B细胞标志物阴性、非特异性酯酶和过氧化物酶反应阴性。初次诊断10个月后，骨髓表现符合急性粒细胞白血病，存在奥氏小体，过氧化物酶阳性、非特异性酯酶阴性、PAS反应阴性。未进行染色体核型分析和显带分析。该患者两种疾病并存的情况在儿科肿瘤学中是独一无二的。