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一名艾滋病患者合并隐球菌性和结核性脑膜炎的神经梅毒:罕见病例报告

Neurosyphilis with Concomitant Cryptococcal and Tuberculous Meningitis in a Patient with AIDS: Report of a Unique Case.

作者信息

Gonzales Zamora Jose Armando, Espinoza Luis Alberto, Nwanyanwu Rita N

机构信息

Division of Infectious Diseases, Department of Medicine, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.

出版信息

Case Rep Infect Dis. 2017;2017:4103858. doi: 10.1155/2017/4103858. Epub 2017 Aug 27.

DOI:10.1155/2017/4103858
PMID:28928997
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5591983/
Abstract

Meningitis in individuals living with acquired immunodeficiency syndrome (AIDS) is most frequently infectious in origin and usually due to opportunistic infections. The most common pathogens are and . causes neurosyphilis and can complicate HIV infections at any time after the initial infection. Simultaneous infections of the central nervous system caused by these pathogens are very uncommon even in the setting of severe immunosuppression. We report the case of a newly diagnosed HIV/AIDS young man who was found to have neurosyphilis with meningitis. After a few weeks of treatment and initiation of antiretroviral therapy, he was also diagnosed with tuberculous meningitis, which was probably unmasked by the development of immune reconstitution inflammatory syndrome (IRIS). To the best of our knowledge, this is the only case of reported neurosyphilis and meningitis caused concomitantly by and

摘要

获得性免疫缺陷综合征(艾滋病)患者的脑膜炎大多源于感染,通常是由机会性感染引起。最常见的病原体是 和 。 可引发神经梅毒,并在初次感染后的任何时候使艾滋病毒感染复杂化。即使在严重免疫抑制的情况下,这些病原体同时感染中枢神经系统的情况也非常罕见。我们报告了一例新诊断的艾滋病毒/艾滋病青年男性病例,该患者被发现患有神经梅毒合并 脑膜炎。经过几周的治疗并开始抗逆转录病毒治疗后,他又被诊断出患有结核性脑膜炎,这可能是由免疫重建炎症综合征(IRIS)的发展而暴露出来的。据我们所知,这是唯一一例报告的由 和 同时引发神经梅毒和脑膜炎的病例

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3781/5591983/61f88c5596b2/CRIID2017-4103858.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3781/5591983/61f88c5596b2/CRIID2017-4103858.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3781/5591983/61f88c5596b2/CRIID2017-4103858.001.jpg

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