Department of Clinical Laboratory, The Fourth People's Hospital of Nanning, Nanning, China.
Key Laboratory of Infectious Diseases, The Fourth People's Hospital of Nanning, Nanning, China.
Medicine (Baltimore). 2024 Oct 25;103(43):e40276. doi: 10.1097/MD.0000000000040276.
Meningitis caused by concurrent infections with Cryptococcus neoformans, Streptococcus equi subsp. equi, and Mycobacterium tuberculosis is extremely rare.
We present the case of a 63-year-old male patient who presented with headaches, dizziness, nausea, vomiting, and fever for the past 3 weeks.
The patient was diagnosed with concurrent cryptococcal, streptococcal, and tuberculous meningitis.
The patient received isoniazid, rifampicin, ethambutol, and levofloxacin for 1 month, in addition to liposomal amphotericin B with flucytosine for 2 weeks, followed by fluconazole with flucytosine for additional 2 weeks.
The symptoms improved, and outpatient therapy was continued.
Infectious meningitis requires a combination of microscopy, culture, and rapid molecular diagnostics for early diagnosis and treatment.
由新型隐球菌、马链球菌马亚种和结核分枝杆菌并发感染引起的脑膜炎极为罕见。
我们报告了一例 63 岁男性患者，该患者因头痛、头晕、恶心、呕吐和发热持续了 3 周。
该患者被诊断为新型隐球菌、马链球菌马亚种和结核分枝杆菌并发脑膜炎。
该患者接受了异烟肼、利福平、乙胺丁醇和左氧氟沙星治疗 1 个月，此外还接受了两性霉素 B 脂质体联合氟胞嘧啶治疗 2 周，然后继续氟康唑联合氟胞嘧啶治疗 2 周。
症状改善，继续门诊治疗。
感染性脑膜炎需要结合显微镜检查、培养和快速分子诊断，以便早期诊断和治疗。
