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内科医生对老年患者药物使用的疑问:2010-2015 年挪威药物信息中心(RELIS)的经验。

Physicians' questions concerning drug use among older patients: experience from Norwegian drug information centres (RELIS) in the period 2010-2015.

机构信息

Section of Clinical Pharmacology, Laboratory of Clinical Biochemistry, Haukeland University Hospital, 5021, Bergen, Norway.

Department of Clinical Science, Faculty of Medicine and Dentistry, University of Bergen, Bergen, Norway.

出版信息

Aging Clin Exp Res. 2018 Jul;30(7):867-870. doi: 10.1007/s40520-017-0832-6. Epub 2017 Sep 19.

DOI:10.1007/s40520-017-0832-6
PMID:28929445
Abstract

Questions from physicians to regional medicines information and pharmacovigilance centres in Norway (RELIS) concerning older patients were described. Question-answer pairs (QAPs) from the RELIS database indexed with the category "older", and concerning individual patients from the period 01 Jan 2010 to 31 Dec 2015, were analysed. Two-hundred and eight QAPs categorized with "older" were retrieved from a total of 16 710 in the study period, and 122 of 208 QAPs fulfilled the inclusion criteria. The most common categories of drugs in question (n = 228) according to the ATC system were N: Nervous system (30.3%) and C: Cardiovascular system (23.7%). Questions from physicians (n = 122) were most frequently about adverse effects (41.8%) and treatment (39.3%). The majority of questions to RELIS concerning older patients came from general practice (GP). The results suggest drug information efforts to GPs in care of older patients with regard to psychopharmacology and cardiovascular pharmacology.

摘要

本文描述了挪威区域药品信息和药物警戒中心(RELIS)接到的关于老年患者的医生咨询问题。对 RELIS 数据库中索引类别为“老年”的 2010 年 1 月 1 日至 2015 年 12 月 31 日期间针对个别患者的问答对(QAP)进行了分析。在研究期间,从总共 16710 个中检索到 208 个分类为“老年”的 QAP,其中 122 个符合纳入标准。根据 ATC 系统,最常见的问题药物类别(n=228)为 N:神经系统(30.3%)和 C:心血管系统(23.7%)。医生提出的(n=122)问题主要集中在不良反应(41.8%)和治疗(39.3%)方面。针对老年患者向 RELIS 提出的问题大多数来自普通科医生(GP)。结果表明,需要针对老年患者的精神药理学和心血管药理学向 GP 提供药物信息方面的支持。

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