Vega-Zelaya L, Torres C V, Navas-Garcia M, Sola R G, Pastor J
Hospital Universitario de la Princesa, 28006 Madrid, Espana.
Rev Neurol. 2017 Oct 1;65(7):322-326.
The response of the thalamus during the study with somatosensory evoked potentials (SSEP) is not sufficiently understood.
A 17-year-old man undergoing surgery for deep brain stimulation in the centromedian nucleus for drug-resistant epilepsy under complete sedation. During the intervention, the responses to SSEPs of the thalamic nuclei were recorded by means of four microelectrodes. These responses can be decomposed into three types: local field potentials (LFP), low amplitude fast oscillations (LFO), and high amplitude slow oscillations (HSO). LFO are widespread in much of the registered regions. However, HSOs are located at a single point in the registry and are closely associated with LFPs.
Although the presence of LFO has been considered as an indicator of the presence of the sensory thalamus, its wide extension by different thalamic nuclei suggests that it is an unspecific response to SSEPs. However, the restricted spatial location of HSO and their association with LFP suggest that these newly described potentials are the markers for the presence of the sensory thalamus. Their identification may prove very useful in thalamic deep brain stimulation either in awake patients or especially in those requiring sedation.
在体感诱发电位（SSEP）研究中，丘脑的反应尚未得到充分理解。
一名17岁男性，在全身麻醉下接受针对耐药性癫痫的丘脑中央中核深部脑刺激手术。在手术过程中，通过四个微电极记录丘脑核团对SSEP的反应。这些反应可分为三种类型：局部场电位（LFP）、低幅快速振荡（LFO）和高幅慢振荡（HSO）。LFO在大部分记录区域广泛存在。然而，HSO位于记录中的单个点，且与LFP密切相关。
尽管LFO的存在被认为是感觉丘脑存在的指标，但其在不同丘脑核团中的广泛分布表明它是对SSEP的非特异性反应。然而，HSO的空间位置受限及其与LFP的关联表明，这些新描述的电位是感觉丘脑存在的标志物。它们的识别可能在清醒患者或特别是需要镇静的患者的丘脑深部脑刺激中非常有用。
