Yokoi Yuma, Narita Zui, Sumiyoshi Tomiki
1 National Center of Neurology and Psychiatry, Tokyo, Japan.
Clin EEG Neurosci. 2018 Mar;49(2):93-102. doi: 10.1177/1550059417732247. Epub 2017 Sep 20.
Transcranial direct current stimulation, one of the neuromodulation paradigms, is attracting interest as a novel method to treat various central nervous system disorders. It is safe, portable, and cost-effective, and has been applied experimentally for patients with various neuropsychiatric conditions. For the clinical importance and preliminary positive results, growing number of randomized controlled trials to patients with depression or schizophrenia are reported, followed by systematic reviews and meta-analyses. However, former research specifically focuses on depression or psychosis in psychiatric disorders. Therefore, we provide a systematic review of studies reporting the effectiveness of transcranial direct current stimulation in ameliorating these symptoms not limited to psychiatric patients or objective scales by examining double-blind sham-controlled trials.
经颅直流电刺激是神经调节模式之一，作为一种治疗各种中枢神经系统疾病的新方法正引起人们的关注。它安全、便携且具有成本效益，已在患有各种神经精神疾病的患者中进行了实验应用。鉴于其临床重要性和初步的积极结果，越来越多针对抑郁症或精神分裂症患者的随机对照试验被报道，随后是系统评价和荟萃分析。然而，以前的研究特别关注精神疾病中的抑郁症或精神病。因此，我们通过审查双盲假对照试验，对报告经颅直流电刺激在改善这些症状（不限于精神病患者或客观量表）方面有效性的研究进行了系统评价。
