远洋性麻痹

Pelagic paralysis.

作者信息

Mills A R, Passmore R

出版信息

Lancet. 1988 Jan 23;1(8578):161-4. doi: 10.1016/s0140-6736(88)92729-8.

Abstract

Three conditions that may occur after consumption of seafood--puffer fish poisoning, ciguatera, and paralytic shellfish poisoning--are caused by a group of poisons that block voltage-gated sodium channels in myelinated and non-myelinated nerves. The conditions cannot be distinguished clinically and so constitute an entity for which the name pelagic paralysis is proposed. Variations in the clinical features can be accounted for by large differences in the amount of toxin present in the seafood.

摘要

食用海鲜后可能出现的三种情况——河豚中毒、雪卡毒素中毒和麻痹性贝类中毒——是由一组能阻断有髓和无髓神经中电压门控钠通道的毒素引起的。这些情况在临床上无法区分，因此构成了一个实体，为此提出了“远洋麻痹”这一名称。临床特征的差异可以用海鲜中所含毒素量的巨大差异来解释。