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利用小波变换检测充血性心力衰竭患者的代偿期和失代偿期。

Use of Wavelet Transform to Detect Compensated and Decompensated Stages in the Congestive Heart Failure Patient.

机构信息

ECEE, University of Colorado, Boulder, CO 80309, USA.

Medicine-Cardiology, School of Medicine, University of Colorado, Denver, CO 80204.

出版信息

Biosensors (Basel). 2017 Sep 20;7(3):40. doi: 10.3390/bios7030040.

Abstract

This research work is aimed at improving health care, reducing cost, and the occurrence of emergency hospitalization in patients with Congestive Heart Failure (CHF) by analyzing heart and lung sounds to distinguish between the compensated and decompensated states. Compensated state defines stable state of the patient but with lack of retention of fluids in lungs, whereas decompensated state leads to unstable state of the patient with lots of fluid retention in the lungs, where the patient needs medication. Acoustic signals from the heart and the lung were analyzed using wavelet transforms to measure changes in the CHF patient's status from the decompensated to compensated and vice versa. Measurements were taken on CHF patients diagnosed to be in compensated and decompensated states by using a digital stethoscope and electrocardiogram (ECG) in order to monitor their progress in the management of their disease. Analysis of acoustic signals of the heart due to the opening and closing of heart valves as well as the acoustic signals of the lungs due to respiration and the ECG signals are presented. Fourier, short-time Fourier, and wavelet transforms are evaluated to determine the best method to detect shifts in the status of a CHF patient. The power spectra obtained through the Fourier transform produced results that differentiate the signals from healthy people and CHF patients, while the short-time Fourier transform (STFT) technique did not provide the desired results. The most promising results were obtained by using wavelet analysis. Wavelet transforms provide better resolution, in time, for higher frequencies, and a better resolution, in frequency, for lower frequencies.

摘要

本研究旨在通过分析心肺声音来区分充血性心力衰竭 (CHF) 患者的代偿和失代偿状态,从而改善医疗保健、降低成本并减少急诊住院的发生。代偿状态定义为患者稳定但肺部无液体潴留,而失代偿状态则导致患者不稳定,肺部有大量液体潴留,需要药物治疗。使用小波变换分析心音和肺音,以测量 CHF 患者从失代偿到代偿和反之的状态变化。使用数字听诊器和心电图 (ECG) 对诊断为代偿和失代偿状态的 CHF 患者进行测量,以监测其疾病管理的进展。分析了由于心脏瓣膜的开闭而产生的心脏声信号以及由于呼吸和 ECG 信号而产生的肺部声信号。评估了傅里叶变换、短时傅里叶变换和小波变换,以确定检测 CHF 患者状态变化的最佳方法。通过傅里叶变换获得的功率谱产生了区分健康人和 CHF 患者信号的结果,而短时傅里叶变换 (STFT) 技术没有提供预期的结果。最有前途的结果是通过使用小波分析获得的。小波变换在时间上提供了更高频率的更好分辨率,在频率上提供了更低频率的更好分辨率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db85/5618046/f8c456966e94/biosensors-07-00040-g001.jpg

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