Department of Cell Biology, Institute for Virus Research, Kyoto University, Sakyo-ku, Kyoto, Japan 606-850,
Department of Viral Oncology, Institute for Virus Research, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan.
Front Biosci (Landmark Ed). 2018 Jan 1;23(3):506-511. doi: 10.2741/4602.
Chromosomal DNA replication machinery is essential for growth of all cells in all organs in multicellular organisms. Its knockdown in several tissues of Drosophila led to rough eye phenotype and the loss of bristles in the eye. These results show that the DNA replication machinery contributes to the body development independent of growth.
染色体 DNA 复制机制对于多细胞生物所有器官中所有细胞的生长都是必不可少的。在果蝇的几个组织中敲低其表达水平,会导致眼睛粗糙表型和眼睛刚毛缺失。这些结果表明,DNA 复制机制在独立于生长的情况下,有助于身体发育。