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非常晚期生物可吸收支架血栓形成以及两年后再发夹层,左前降支慢性完全闭塞再通。

Very late bioresorbable scaffold thrombosis and reoccurrence of dissection two years later chronic total occlusion recanalization of the left anterior descending artery.

作者信息

Di Serafino Luigi, Cirillo Plinio, Niglio Tullio, Borgia Francesco, Trimarco Bruno, Esposito Giovanni, Stabile Eugenio

机构信息

Division of Cardiology, Department of Advanced Biomedical Sciences, University of Naples "Federico II", 80131 Naples, Italy.

出版信息

World J Cardiol. 2017 Aug 26;9(8):710-714. doi: 10.4330/wjc.v9.i8.710.

DOI:10.4330/wjc.v9.i8.710
PMID:28932360
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5583544/
Abstract

We describe the case of a patient presenting with ST-segment elevation myocardial infarction due to very late scaffold thrombosis. The patient was already admitted for an elective percutaneous recanalization of a chronically occluded left anterior descending artery (LAD). The procedure was performed according the sub-intimal tracking and re-entry (STAR) technique with 4 bioresorbable vascular scaffolds implantation. However, even though the coronary flow was preserved at the end of the procedure, the dissected segment was only partially sealed at the distal segment of the LAD. After 18 mo of regular assumption, dual antiplatelet therapy was discontinued for 10 mo before his presentation at the emergency room. This is the first reported case of a very late scaffold thrombosis after coronary chronic total occlusion (CTO) recanalization performed according to the STAR technique. This case raises concerns about the risk of very late scaffold thrombosis after complex CTO revascularization.

摘要

我们描述了一例因极晚期支架内血栓形成导致ST段抬高型心肌梗死的患者。该患者已因择期对慢性闭塞的左前降支(LAD)进行经皮再通而入院。手术按照内膜下追踪和重新进入(STAR)技术进行,植入了4个生物可吸收血管支架。然而,尽管手术结束时冠状动脉血流得以保留,但LAD远端的夹层段仅部分封闭。在规律服用药物18个月后,双联抗血小板治疗在他急诊就诊前中断了10个月。这是首例报道的按照STAR技术进行冠状动脉慢性完全闭塞(CTO)再通术后极晚期支架内血栓形成的病例。该病例引发了对复杂CTO血运重建术后极晚期支架内血栓形成风险的关注。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1066/5583544/ccd93153b0e0/WJC-9-710-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1066/5583544/a55cafee95e9/WJC-9-710-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1066/5583544/fdc1e234ba2a/WJC-9-710-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1066/5583544/ccd93153b0e0/WJC-9-710-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1066/5583544/a55cafee95e9/WJC-9-710-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1066/5583544/fdc1e234ba2a/WJC-9-710-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1066/5583544/ccd93153b0e0/WJC-9-710-g003.jpg

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本文引用的文献

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Antiplatelet Therapy After Implantation of Bioresorbable Vascular Scaffolds: A Review of the Published Data, Practical Recommendations, and Future Directions.生物可吸收血管支架置入后抗血小板治疗:文献回顾、实用建议及未来方向
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Very Late Bioresorbable Scaffold Thrombosis Caused by Intraluminal Scaffold Dismantling.腔内支架拆解导致的极晚期生物可吸收支架血栓形成
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Very Late Scaffold Thrombosis: Intracoronary Imaging and Histopathological and Spectroscopic Findings.极晚期支架血栓:冠状动脉内影像学及组织病理学和光谱学研究结果。
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