Day R, Akil H
Mental Health Research Institute, University of Michigan, Ann Arbor 48109-0720.
NIDA Res Monogr. 1986;75:244-6.
Bridge peptide, the sequence of amino acids which joins alpha-neo-endorphin and dynorphin A 1-17, was determined to exist as a free molecule in the rat anterior pituitary. Gel filtration chromatography revealed the presence of the free peptide as well as a high molecular weight intermediate of 8-9 kilodaltons.
桥接肽是连接α-新内啡肽和强啡肽A 1-17的氨基酸序列,已确定其在大鼠垂体前叶中以游离分子形式存在。凝胶过滤色谱显示存在游离肽以及一种8至9千道尔顿的高分子量中间体。