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[人参属植物转录组学研究进展]

[Advance in transcriptomic studies of ginseng species].

作者信息

Zou Li-Qiu, Kuang Xue-Jun, Li Ying, Sun Chao

机构信息

Institute of Medicinal Plant Development, China Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2016 Nov;41(22):4138-4143. doi: 10.4268/cjcmm20162209.

Abstract

There are many valuable medicinal plants in Ginseng genus belonging to Araliaceae. Among them, Panax ginseng, P. quinquefolium and P. notoginseng are the most famous species. With the development of next-generation sequencing (NGS) technologies, sequencing and analysis of transcriptomes have become powerful tools for discovery of novel genes, screening molecular markers and elucidation of specific biosynthetic pathway of secondary metabolites. Their transcriptomes provided abundant genes for further study on functional genomics. Here this paper summarized the recent advances in the transcriptomic studies of these three medicinal plants, including discovery of novel genes and elucidation of metabolic regulation, which will contribute to functional genomics in ginseng species.

摘要

五加科人参属中有许多珍贵的药用植物。其中,人参、西洋参和三七是最著名的种类。随着新一代测序(NGS)技术的发展,转录组测序和分析已成为发现新基因、筛选分子标记以及阐明次生代谢物特定生物合成途径的有力工具。它们的转录组为功能基因组学的进一步研究提供了丰富的基因。本文综述了这三种药用植物转录组学研究的最新进展,包括新基因的发现和代谢调控的阐明,这将有助于人参属植物的功能基因组学研究。

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