Tengs Torstein, Jonassen Christine M
Norwegian Veterinary Institute, Ullevaalsveien 68, 0454 Oslo, Norway.
Centre for Laboratory Medicine, Østfold Hospital Trust, Kalnesveien 300, 1714 Grålum, Norway.
Diseases. 2016 Jul 28;4(3):27. doi: 10.3390/diseases4030027.
The mobile genetic element s2m has been described in several families of single-stranded RNA viruses. The function remains elusive, but an increasing number of s2m-containing sequences are being deposited in publicly available databases. Currently, more than 700 coronavirus sequences containing s2m can be found in GenBank, including the severe acute respiratory syndrome (SARS) coronavirus genome. This is an updated review of the pattern of s2m in coronaviruses, the possible functional implications and the evolutionary history.
移动遗传元件s2m已在几个单链RNA病毒家族中被描述。其功能仍然难以捉摸，但越来越多含有s2m的序列被存入公开可用的数据库中。目前，在GenBank中可以找到700多个含有s2m的冠状病毒序列，包括严重急性呼吸综合征（SARS）冠状病毒基因组。这是一篇关于冠状病毒中s2m模式、可能的功能影响和进化历史的更新综述。
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