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新生儿皮下脂肪坏死伴初发低钙血症和家族性复发:病例报告。

Subcutaneous Fat Necrosis of the Newborn With Initial Hypocalcemia and Familial Recurrence: A Case Report.

机构信息

1 Division of Paediatric Medicine, Department of Paediatrics, Hospital for Sick Children, Toronto, ON, Canada.

2 Child Health Evaluative Sciences, Sickkids Research Institute, Toronto, ON, Canada.

出版信息

J Cutan Med Surg. 2018 Mar/Apr;22(2):223-225. doi: 10.1177/1203475417733459. Epub 2017 Sep 21.

Abstract

Subcutaneous fat necrosis of the newborn (SFNN) is a rare disorder characterised by indurated plaques or nodules with or without erythema, typically distributed over the cheeks, extremities, posterior trunk, buttocks, and thighs, and appears during the first 2 weeks of life. It is commonly associated with perinatal asphyxia and, while usually self-limited, can lead to severe hypercalcemia. There is no known familial association. The present article describes a neonate with extensive disease, counterintuitive hypocalcemia, and a family history of SFNN and reviews the existing literature on SFNN.

摘要

新生儿皮下脂肪坏死(SFNN)是一种罕见的疾病,其特征为硬结性斑块或结节,可伴有或不伴有红斑,通常分布于面颊、四肢、躯干后部、臀部和大腿,在生命的头 2 周内出现。它通常与围产期窒息有关,虽然通常是自限性的,但可导致严重的高钙血症。目前尚无家族相关性的报道。本文描述了一例广泛发病、与临床不符的低钙血症新生儿,且存在 SFNN 家族史,并对现有关于 SFNN 的文献进行了回顾。

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