1 Division of Paediatric Medicine, Department of Paediatrics, Hospital for Sick Children, Toronto, ON, Canada.
2 Child Health Evaluative Sciences, Sickkids Research Institute, Toronto, ON, Canada.
J Cutan Med Surg. 2018 Mar/Apr;22(2):223-225. doi: 10.1177/1203475417733459. Epub 2017 Sep 21.
Subcutaneous fat necrosis of the newborn (SFNN) is a rare disorder characterised by indurated plaques or nodules with or without erythema, typically distributed over the cheeks, extremities, posterior trunk, buttocks, and thighs, and appears during the first 2 weeks of life. It is commonly associated with perinatal asphyxia and, while usually self-limited, can lead to severe hypercalcemia. There is no known familial association. The present article describes a neonate with extensive disease, counterintuitive hypocalcemia, and a family history of SFNN and reviews the existing literature on SFNN.
新生儿皮下脂肪坏死（SFNN）是一种罕见的疾病，其特征为硬结性斑块或结节，可伴有或不伴有红斑，通常分布于面颊、四肢、躯干后部、臀部和大腿，在生命的头 2 周内出现。它通常与围产期窒息有关，虽然通常是自限性的，但可导致严重的高钙血症。目前尚无家族相关性的报道。本文描述了一例广泛发病、与临床不符的低钙血症新生儿，且存在 SFNN 家族史，并对现有关于 SFNN 的文献进行了回顾。
