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[支气管支架植入联合化疗及阿帕替尼成功治疗1例发生支气管转移的直肠癌患者的报告]

[Report of Successful Treatment of A Rectal Cancer Patient with Endobronchial 
Metastasis by Bronchial Stent Implantation Combined with Chemotherapy and Apatinib].

作者信息

Lin Qiuqi, Ding Ling, Chen Cheng, Zhu Yehan

机构信息

Department of Respiratory Medicine, the First Affiliated Hospital of Soochow University, Suzhou 215006, China.

出版信息

Zhongguo Fei Ai Za Zhi. 2017 Sep 20;20(9):657-660. doi: 10.3779/j.issn.1009-3419.2017.09.12.

DOI:10.3779/j.issn.1009-3419.2017.09.12
PMID:28935022
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5973369/
Abstract

The lungs are the most common sites of metastases from non-pulmonary malignancies. On the other hand, endobronchial metastases are rare. Various tumors have been associated with endobronchial metastasis, most commonly renal, breast and colorectal cancer. Advanced rectal cancerwith lung metastasis is common. However, endobronchial metastasis without lung metastasis of rectal cancer is rare, and easily misdiagnosed. We report one case of postoperative rectal cancer with endobronchial, pleuralcavity, pericardial cavitymetastasis, giving the comprehensive treatment of bronchial stentimplantation, chemotherapy, targeted drugs and remission. The process of diagnosis and treatmentis relatively complex, therefore it has a certain clinical reference value.

摘要

肺是非肺恶性肿瘤最常见的转移部位。另一方面,支气管内转移很少见。多种肿瘤与支气管内转移有关,最常见的是肾癌、乳腺癌和结直肠癌。晚期直肠癌伴肺转移很常见。然而,直肠癌无肺转移的支气管内转移很少见,且容易误诊。我们报告1例术后直肠癌发生支气管内、胸腔、心包腔转移的病例,给予支气管支架植入、化疗、靶向药物等综合治疗后病情缓解。其诊治过程较为复杂,因此具有一定的临床参考价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6201/5973369/4c2023e1bdb8/zgfazz-20-9-657-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6201/5973369/8b4bdc95a96c/zgfazz-20-9-657-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6201/5973369/dd7959b85fa0/zgfazz-20-9-657-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6201/5973369/63c98ff1074a/zgfazz-20-9-657-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6201/5973369/4c2023e1bdb8/zgfazz-20-9-657-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6201/5973369/8b4bdc95a96c/zgfazz-20-9-657-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6201/5973369/dd7959b85fa0/zgfazz-20-9-657-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6201/5973369/63c98ff1074a/zgfazz-20-9-657-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6201/5973369/4c2023e1bdb8/zgfazz-20-9-657-4.jpg

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本文引用的文献

1
Endobronchial metastasis: an epidemiologic and clinicopathologic study of 174 consecutive cases.支气管内转移:174 例连续病例的流行病学和临床病理研究。
Lung Cancer. 2014 Jun;84(3):222-8. doi: 10.1016/j.lungcan.2014.03.005. Epub 2014 Mar 13.
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Safety and pharmacokinetics of novel selective vascular endothelial growth factor receptor-2 inhibitor YN968D1 in patients with advanced malignancies.新型选择性血管内皮生长因子受体-2 抑制剂 YN968D1 在晚期恶性肿瘤患者中的安全性和药代动力学。
BMC Cancer. 2010 Oct 5;10:529. doi: 10.1186/1471-2407-10-529.
3
Endobronchial metastases from colorectal cancers: natural history and role of interventional bronchoscopy.
结直肠癌的支气管内转移:自然病史及介入性支气管镜检查的作用
Respiration. 2009;77(1):63-9. doi: 10.1159/000158487. Epub 2008 Sep 24.
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Endobronchial metastases from extrathoracic malignancies.胸外恶性肿瘤的支气管内转移
Clin Exp Metastasis. 2005;22(7):587-91. doi: 10.1007/s10585-005-5787-x. Epub 2006 Feb 11.
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Endobronchial metastases from extrapulmonary solid tumors.肺外实体瘤的支气管内转移
Acta Oncol. 2004;43(1):73-9. doi: 10.1080/02841860310018053.
6
Endoscopic treatment of malignant airway obstructions in 2,008 patients.2008例恶性气道梗阻的内镜治疗
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