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急性摄入咖啡因对糖尿病患者胰岛素敏感性和血糖控制的影响。

The effect of acute caffeine intake on insulin sensitivity and glycemic control in people with diabetes.

作者信息

Dewar Lisa, Heuberger Roschelle

机构信息

2004 Taylor St, San Francisco, CA, 94133, United States.

Department of Human Environmental Studies, Central Michigan University, Mt Pleasant, MI, 48859, United States.

出版信息

Diabetes Metab Syndr. 2017 Dec;11 Suppl 2:S631-S635. doi: 10.1016/j.dsx.2017.04.017. Epub 2017 Apr 23.

Abstract

The prevalence of diabetes is growing globally, and with no current cure for the disease, management is focused on optimizing blood glucose control to limit complications. The purpose of this review was to examine the effect of caffeine intake on blood glucose levels in people with diabetes. Electronic searches were completed using Pub Med, CINAHL, and Web of Science using the search terms "coffee and insulin," "caffeine and insulin," "caffeine and diabetes," "caffeine and type 1 diabetes," "caffeine and type 2 diabetes," and "caffeine and glycemia." Seven trials were found to meet the search criteria. Five of the 7 studies suggest caffeine intake increases blood glucose levels, and prolongs the period of high blood glucose levels. Future research should focus on larger clinical trials to confirm the relationship and mechanism of action related to caffeine intake and glycemic control in individuals with diabetes.

摘要

糖尿病在全球的患病率正在上升,而且目前尚无治愈该疾病的方法,管理重点在于优化血糖控制以限制并发症。本综述的目的是研究咖啡因摄入对糖尿病患者血糖水平的影响。使用搜索词“咖啡与胰岛素”“咖啡因与胰岛素”“咖啡因与糖尿病”“咖啡因与1型糖尿病”“咖啡因与2型糖尿病”以及“咖啡因与血糖”,通过PubMed、CINAHL和科学网完成了电子检索。发现有7项试验符合检索标准。7项研究中的5项表明,摄入咖啡因会使血糖水平升高,并延长高血糖水平的持续时间。未来的研究应侧重于更大规模的临床试验,以证实糖尿病患者咖啡因摄入与血糖控制之间的关系及作用机制。

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