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2017年南非一群溶血性尿毒症综合征病例所关联的产志贺毒素O26:H11的基因组序列

Genome Sequence for Shiga Toxin-Producing O26:H11, Associated with a Cluster of Hemolytic-Uremic Syndrome Cases in South Africa, 2017.

作者信息

Smith Anthony M, Bosco Kalule J, Nicol Mark P, Kleynhans Jackie, McCulloch Mignon, Duze Sanelisiwe T, Ismail Arshad, Allam Mushal, Tau Nomsa P, Keddy Karen H

机构信息

Centre for Enteric Diseases, National Institute for Communicable Diseases, National Health Laboratory Service, Johannesburg, South Africa

Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

出版信息

Genome Announc. 2017 Sep 21;5(38):e00989-17. doi: 10.1128/genomeA.00989-17.

Abstract

Shiga toxin-producing (STEC) strains are primarily foodborne pathogens that may cause diarrheal outbreaks and are associated with severe complications, specifically hemolytic-uremic syndrome (HUS). We report here genome sequence data for STEC O26:H11, which is associated with a cluster of cases of HUS, a rarely described syndrome in South Africa.

摘要

产志贺毒素大肠杆菌(STEC)菌株主要是食源性病原体,可引发腹泻疫情,并与严重并发症相关,尤其是溶血尿毒综合征(HUS)。我们在此报告STEC O26:H11的基因组序列数据,该菌株与一组HUS病例有关,HUS在南非是一种鲜有描述的综合征。

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