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Understanding adherence to medications in type 2 diabetes care and clinical trials to overcome barriers: a narrative review.了解2型糖尿病护理和临床试验中药物治疗的依从性以克服障碍:一项叙述性综述
Curr Med Res Opin. 2016;32(2):277-87. doi: 10.1185/03007995.2015.1119677. Epub 2015 Dec 2.
2
Medication adherence and direct treatment cost among diabetes patients attending a tertiary healthcare facility in Ogbomosho, Nigeria.尼日利亚奥格博莫索一家三级医疗机构中糖尿病患者的药物依从性和直接治疗费用。
Malawi Med J. 2015 Jun;27(2):65-70. doi: 10.4314/mmj.v27i2.7.
3
Patterns and obstacles to oral antidiabetic medications adherence among type 2 diabetics in Ismailia, Egypt: a cross section study.埃及伊斯梅利亚2型糖尿病患者口服抗糖尿病药物依从性的模式与障碍:一项横断面研究
Pan Afr Med J. 2015 Feb 25;20:177. doi: 10.11604/pamj.2015.20.177.4025. eCollection 2015.
4
Nonadherence and contributing factors among ambulatory patients with antidiabetic medications in Adama Referral Hospital.阿达马转诊医院门诊糖尿病患者的抗糖尿病药物治疗依从性及相关因素
J Diabetes Res. 2014;2014:617041. doi: 10.1155/2014/617041. Epub 2014 Dec 3.
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Patients' Adherence to Anti-Diabetic Medications in a Hospital at Ajman, UAE.阿联酋阿治曼一家医院中患者对抗糖尿病药物的依从性
Malays J Med Sci. 2014 Jan;21(1):44-9.
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Measuring the rate of therapeutic adherence among outpatients with T2DM in Egypt.测量埃及 2 型糖尿病门诊患者的治疗依从率。
Saudi Pharm J. 2010 Oct;18(4):225-32. doi: 10.1016/j.jsps.2010.07.004. Epub 2010 Jul 30.
7
Factors contributing to non-compliance among diabetics attending primary health centers in the Al Hasa district of Saudi Arabia.沙特阿拉伯胡富夫地区基层医疗中心糖尿病患者治疗依从性不佳的相关因素。
J Family Community Med. 2012 Jan;19(1):26-32. doi: 10.4103/2230-8229.94008.
8
Medication adherence in diabetes mellitus and self management practices among type-2 diabetics in Ethiopia.埃塞俄比亚2型糖尿病患者的糖尿病药物依从性及自我管理实践
N Am J Med Sci. 2011 Sep;3(9):418-23. doi: 10.4297/najms.2011.3418.
9
Adherence and satisfaction with oral hypoglycemic medications: a pilot study in Palestine.口服降糖药的依从性和满意度:巴勒斯坦的一项试点研究。
Int J Clin Pharm. 2011 Dec;33(6):942-8. doi: 10.1007/s11096-011-9561-7. Epub 2011 Sep 15.
10
Predictive validity of a medication adherence measure in an outpatient setting.门诊环境中药物依从性测量的预测效度。
J Clin Hypertens (Greenwich). 2008 May;10(5):348-54. doi: 10.1111/j.1751-7176.2008.07572.x.

沙特阿拉伯糖尿病患者口服降糖药物的依从性

Adherence to oral hypoglycemic medication among patients with diabetes in Saudi Arabia.

作者信息

Ahmed Nahid Osman, Abugalambo Salwa, Almethen Ghadeer Hamad

机构信息

Department of Pharmacy Practice, Faculty of Pharmacy, Qassim University, Kingdom of Saudi Arabia.

Department of Pharmacy Practice, Qassim University, Kingdom of Saudi Arabia.

出版信息

Int J Health Sci (Qassim). 2017 Jul-Sep;11(3):45-49.

PMID:28936151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5604262/
Abstract

INTRODUCTION

Diabetes mellitus is a chronic progressive disease characterized by numerous health complications. Medication adherence is an important determinant of therapeutic outcome. The objective of this study was to assess hypoglycemic medication adherence.

MATERIALS AND METHODS

This is a descriptive cross-sectional web-based study. The eight-item Morisky medication adherence scale was used to assess adherence.

RESULTS

A convenience sample of 290 patients with diabetes was studied; of them, 10.7% had a high adherence, 34.5% had a medium adherence, and 54.8% had a low adherence level. Adherence score was a positively and significantly correlated with age ( < 0.05). Similar significant correlation was found between adherence level and gender ( < 0.05). However, adherence was not significantly associated with diabetes duration of disease ( > 0.05) and number of hypoglycemic medications ( >0.05).

CONCLUSION

The majority of patients with diabetes in this study had low adherence rate. The three main factors may contribute to non-adherence to medication are non-adherence to regular follow-up in diabetes clinic, non-adherence to healthy diet, and non-adherence to instruction to take medication.

摘要

引言

糖尿病是一种慢性进行性疾病,其特征为出现众多健康并发症。药物依从性是治疗结果的一个重要决定因素。本研究的目的是评估降糖药物的依从性。

材料与方法

这是一项基于网络的描述性横断面研究。采用八项Morisky药物依从性量表来评估依从性。

结果

对290例糖尿病患者的便利样本进行了研究;其中,10.7%具有高依从性,34.5%具有中等依从性,54.8%具有低依从性水平。依从性得分与年龄呈正相关且具有显著性(<0.05)。在依从性水平与性别之间也发现了类似的显著相关性(<0.05)。然而,依从性与糖尿病病程(>0.05)和降糖药物数量(>0.05)无显著关联。

结论

本研究中大多数糖尿病患者的依从率较低。导致不依从药物治疗的三个主要因素可能是未坚持在糖尿病门诊定期随访、未坚持健康饮食以及未坚持服药说明。