自主神经系统对大鼠下颌下唾液腺蛋白质分泌的影响。

Autonomic effects on protein secretion by rat submandibular salivary glands.

Abe K

Department of Oral Biochemistry, Fukuoka Dental College.

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1987;88(2):241-8. doi: 10.1016/0742-8413(87)90116-2.

Abstract

Following treatment with cholinergic and beta-adrenergic drugs, the beta-type protein, associated with cAMP, was secreted regardless of the doses used. 2. Following treatment with alpha 1-adrenergic drugs, both the beta-type and alpha-type proteins were secreted depending on the doses used and the alpha-type protein was completely converted to the beta-type with alpha-blockers. 3. Following treatment with alpha 2-adrenergic drugs, the gamma-type protein, associated with cGMP, was secreted independent of the doses used.

摘要

用胆碱能药物和β-肾上腺素能药物治疗后，与环磷酸腺苷（cAMP）相关的β型蛋白会分泌出来，且与所用剂量无关。2. 用α1-肾上腺素能药物治疗后，β型和α型蛋白都会分泌，这取决于所用剂量，并且α型蛋白会被α受体阻滞剂完全转化为β型。3. 用α2-肾上腺素能药物治疗后，与环磷酸鸟苷（cGMP）相关的γ型蛋白会分泌出来，与所用剂量无关。