Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Mount Sinai Hospital, New York, New York, USA.
Kidney Int. 2017 Oct;92(4):793-795. doi: 10.1016/j.kint.2017.05.030.
APOL1 risk variants have been shown to be associated with kidney disease and hypertension. In this study, Chen and colleagues assess the association of these risk variants with longitudinal blood pressure in young adults. We review the current literature on association of these alleles with blood pressure and propose future directions to resolve the existing controversies.
APOL1 风险变异与肾脏疾病和高血压有关。在这项研究中，Chen 及其同事评估了这些风险变异与年轻人纵向血压的关联。我们回顾了目前关于这些等位基因与血压关联的文献，并提出了未来解决现有争议的方向。
