Praxis für MKG-Chirurgie (Head: Dr. Dr. Frank Halling), Gesundheitszentrum Fulda, Gerloser Weg 23a, D-36039 Fulda, Germany; Dept. of Maxillofacial Surgery (Head: Prof. Dr. Dr. Andreas Neff), University Hospital, Baldingerstr, D-35043 Marburg, Germany.
Dept. of Maxillofacial Surgery (Head: Prof. Dr. Dr. Andreas Neff), University Hospital, Baldingerstr, D-35043 Marburg, Germany.
J Craniomaxillofac Surg. 2017 Nov;45(11):1854-1859. doi: 10.1016/j.jcms.2017.08.010. Epub 2017 Aug 19.
To analyze the structure of antibiotic prescriptions by dentists in Germany during a time-period of four years in relation to medical antibiotic prescriptions.
We collected nationwide data from all statutory health insurances on dental prescriptions of systemic antibiotics from 2012 to 2015. The annual reports of the "Research Institute for Local Health Care Systems" (WIdO, Berlin) provided the basis for this longitudinal data base analysis. The types of antibiotics, the number of prescriptions and the prescribed 'defined daily doses' (DDD) were analyzed. The results were compared to antibiotic prescriptions of German physicians.
An average of 8.8% per year of all antibiotic prescriptions is issued by dentists. The mostly prescribed antibiotic is amoxicillin. The share of amoxicillin on all dental prescriptions increased from 35.6% in 2012 to 45.8% in 2015 (p < 0.01). About three-quarters of all dentally prescribed DDD can be attributed to amoxicillin and clindamycin. On the part of the physicians the proportion of clindamycin is 18 fold lower than in the dental field.
Dental and medical antibiotic prescriptions in Germany show statistically significant differences regarding the shares of the prescribed antibiotics. In an international comparison the high proportion of Clindamycin in Germany is noticeable.
分析德国牙医在四年内开具的抗生素处方结构，并与医学抗生素处方进行比较。
我们从 2012 年至 2015 年期间，从所有法定健康保险中收集了全国范围内的系统性抗生素牙科处方数据。柏林“地方卫生保健系统研究所”（WIdO）的年度报告为这项纵向数据库分析提供了基础。我们分析了抗生素的类型、处方数量和规定的“限定日剂量”（DDD）。结果与德国医生开具的抗生素处方进行了比较。
牙医开具的抗生素处方平均每年占所有抗生素处方的 8.8%。最常开的抗生素是阿莫西林。阿莫西林在所有牙科处方中的份额从 2012 年的 35.6%增加到 2015 年的 45.8%（p<0.01）。约四分之三的牙科规定 DDD 可归因于阿莫西林和克林霉素。在医生处方中，克林霉素的比例比牙科领域低 18 倍。
德国牙医和医生开具的抗生素处方在规定抗生素的比例方面存在统计学上的显著差异。在国际比较中，德国克林霉素的高比例引人注目。
