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基于网络的神经性贪食症女性住院治疗后的随访护理:随机对照疗效试验

Web-Based Aftercare for Women With Bulimia Nervosa Following Inpatient Treatment: Randomized Controlled Efficacy Trial.

作者信息

Jacobi Corinna, Beintner Ina, Fittig Eike, Trockel Mickey, Braks Karsten, Schade-Brittinger Carmen, Dempfle Astrid

机构信息

Institut für Klinische Psychologie und Psychotherapie, Professur Klinische Psychologie & E-Mental Health, Technische Universität Dresden, Dresden, Germany.

Celenus Klinik Carolabad, Medizinisches Rehabilitationszentrum für Psychotherapie, Psychiatrie und Psychosomatik, Chemnitz, Germany.

出版信息

J Med Internet Res. 2017 Sep 22;19(9):e321. doi: 10.2196/jmir.7668.

Abstract

BACKGROUND

Relapse rates in bulimia nervosa (BN) are high even after successful treatment, but patients often hesitate to take up further treatment. An easily accessible program might help maintain treatment gains. Encouraged by the effects of Web-based eating disorder prevention programs, we developed a manualized, Web-based aftercare program (IN@) for women with BN following inpatient treatment.

OBJECTIVE

The objective of this study was to determine the efficacy of the web-based guided, 9-month, cognitive-behavioral aftercare program IN@ for women with BN following inpatient treatment.

METHODS

We conducted a randomized controlled efficacy trial in 253 women with DSM-IV (Diagnostic and Statistical Manual of Mental Disorders, fourth edition) BN and compared the results of IN@ with treatment as usual (TAU). Assessments were carried out at hospital admission (T0), hospital discharge/baseline (T1), postintervention (T2; 9 months after baseline), 9-month follow-up (T3; 18 months after baseline). The primary outcome, abstinence from binge eating and compensatory behaviors during the 2 months preceding T2, was analyzed by intention to treat, using logistic regression analyses. Frequencies of binge eating and vomiting episodes, and episodes of all compensatory behaviors were analyzed using mixed effects models.

RESULTS

At T2, data from 167 women were available. There were no significant differences in abstinence rates between the TAU group (n=24, 18.9%) and the IN@ group (n=27, 21.4%; odds ratio, OR=1.29; P=.44). The frequency of vomiting episodes in the IN@ group was significantly (46%) lower than in the TAU group (P=.003). Moderator analyses revealed that both at T2 and T3, women of the intervention group who still reported binge eating and compensatory behaviors after inpatient treatment benefited from IN@, whereas women who were already abstinent after the inpatient treatment did not (P=.004; P=.002). Additional treatment utilization was high in both groups between baseline and follow-up.

CONCLUSIONS

Overall, data from this study suggest moderate effects of IN@. High rates of outpatient treatment utilization after inpatient treatment may have obscured potential intervention effects on abstinence. An aftercare intervention might be more beneficial as part of a stepped-care approach.

TRIAL REGISTRATION

International Standard Randomized Controlled Trial Number (ISRCTN): 08870215; http://www.isrctn.com/ISRCTN08870215 (Archived by WebCite at http://www.webcitation.org/6soA5bIit).

摘要

背景

神经性贪食症(BN)即使在成功治疗后复发率仍很高,但患者往往不愿接受进一步治疗。一个易于获取的项目可能有助于维持治疗效果。受基于网络的饮食失调预防项目效果的鼓舞,我们为住院治疗后的BN女性患者开发了一个手册化的、基于网络的后续护理项目(IN@)。

目的

本研究的目的是确定基于网络的、为期9个月的认知行为后续护理项目IN@对住院治疗后的BN女性患者的疗效。

方法

我们对253名患有DSM-IV(《精神疾病诊断与统计手册》第四版)BN的女性进行了一项随机对照疗效试验,并将IN@的结果与常规治疗(TAU)进行了比较。在入院时(T0)、出院/基线时(T1)、干预后(T2;基线后9个月)、9个月随访时(T3;基线后18个月)进行评估。主要结局是在T2前2个月内无暴饮暴食和代偿行为,采用意向性分析,使用逻辑回归分析。使用混合效应模型分析暴饮暴食和呕吐发作的频率以及所有代偿行为的发作情况。

结果

在T2时,有167名女性的数据可用。TAU组(n = 24,18.9%)和IN@组(n = 27,21.4%;优势比,OR = 1.29;P = 0.44)的戒断率无显著差异。IN@组的呕吐发作频率显著低于TAU组(46%)(P = 0.003)。调节分析显示,在T

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2df0/5630693/377a44fff905/jmir_v19i9e321_fig1.jpg

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