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一项针对神经性贪食症的精神分析心理治疗或认知行为治疗的随机对照试验。

A randomized controlled trial of psychoanalytic psychotherapy or cognitive-behavioral therapy for bulimia nervosa.

出版信息

Am J Psychiatry. 2014 Jan;171(1):109-16. doi: 10.1176/appi.ajp.2013.12121511.

Abstract

OBJECTIVE

The authors compared psychoanalytic psychotherapy and cognitive-behavioral therapy (CBT) in the treatment of bulimia nervosa.

METHOD

A randomized controlled trial was conducted in which 70 patients with bulimia nervosa received either 2 years of weekly psychoanalytic psychotherapy or 20 sessions of CBT over 5 months. The main outcome measure was the Eating Disorder Examination interview, which was administered blind to treatment condition at baseline, after 5 months, and after 2 years. The primary outcome analyses were conducted using logistic regression analysis.

RESULTS

Both treatments resulted in improvement, but a marked difference was observed between CBT and psychoanalytic psychotherapy. After 5 months, 42% of patients in CBT (N=36) and 6% of patients in psychoanalytic psychotherapy (N=34) had stopped binge eating and purging (odds ratio=13.40, 95% confidence interval [CI]=2.45-73.42; p<0.01). At 2 years, 44% in the CBT group and 15% in the psychoanalytic psychotherapy group had stopped binge eating and purging (odds ratio=4.34, 95% CI=1.33-14.21; p=0.02). By the end of both treatments, substantial improvements in eating disorder features and general psychopathology were observed, but in general these changes took place more rapidly in CBT.

CONCLUSIONS

Despite the marked disparity in the number of treatment sessions and the duration of treatment, CBT was more effective in relieving binging and purging than psychoanalytic psychotherapy and was generally faster in alleviating eating disorder features and general psychopathology. The findings indicate the need to develop and test a more structured and symptom-focused version of psychoanalytic psychotherapy for bulimia nervosa.

摘要

目的

作者比较了精神分析心理疗法和认知行为疗法(CBT)治疗神经性贪食症的效果。

方法

进行了一项随机对照试验,70 名神经性贪食症患者分别接受为期 2 年的每周精神分析心理疗法或 5 个月内 20 次的 CBT。主要观察指标为进食障碍检查访谈,该指标在基线时、5 个月后和 2 年后进行盲法评估,以评估治疗情况。主要的分析采用逻辑回归分析。

结果

两种治疗方法均有改善,但 CBT 和精神分析心理疗法之间存在显著差异。5 个月后,CBT 组 42%(36 例)的患者和精神分析心理疗法组 6%(34 例)的患者停止了暴食和催吐(优势比=13.40,95%置信区间[CI]=2.45-73.42;p<0.01)。2 年后,CBT 组 44%和精神分析心理疗法组 15%的患者停止了暴食和催吐(优势比=4.34,95% CI=1.33-14.21;p=0.02)。在两种治疗结束时,进食障碍特征和一般精神病理学都有显著改善,但总体而言,CBT 更快地发生这些变化。

结论

尽管治疗次数和治疗时间存在显著差异,但 CBT 在缓解暴食和催吐方面比精神分析心理疗法更有效,并且在缓解进食障碍特征和一般精神病理学方面通常更快。这些发现表明需要开发和测试一种更具结构性和以症状为中心的精神分析心理疗法来治疗神经性贪食症。

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