Department of Behavioral Sciences, Stanford University School of Medicine, Stanford, California.
Int J Eat Disord. 2013 Dec;46(8):771-8. doi: 10.1002/eat.22175. Epub 2013 Aug 14.
To examine the predictive value of end of treatment (EOT) outcomes for longer term recovery status.
We used signal detection analysis to identify the best predictors of recovery based on outcome at EOT using five different eating disorder samples from randomized clinical treatment trials. We utilized a transdiagnostic definition of recovery that included normalization of weight and eating related psychopathology.
Achieving a body weight of 95.2% of expected body weight by EOT is the best predictor of recovery for adolescents with anorexia nervosa (AN). For adults with AN, the most efficient predictor of weight recovery (BMI > 19) was weight gain to greater than 85.8% of ideal body weight. In addition, for adults with AN, the most efficient predictor of psychological recovery was achievement of an eating disorder examination (EDE) weight concerns score below 1.8. The best predictor of recovery for adults with Bulimia Nervosa (BN) was a frequency of compensatory behaviors less than two times a month. For adolescents with BN, abstinence from purging and reduction in the EDE restraint score of more than 3.4 from baseline to EOT were good predictors of recovery. For adults with binge eating disorder, reduction of the Global EDE score to within the normal range (<1.58) was the best predictor of recovery.
The relationship between EOT response and recovery remains understudied. Utilizing a transdiagnostic definition of recovery, no uniform predictors were identified across all eating disorder diagnostic groups.
探讨治疗结束(EOT)结局对长期康复状态的预测价值。
我们使用信号检测分析,根据来自随机临床治疗试验的五个不同饮食失调样本在 EOT 时的结果,确定基于恢复的最佳预测因子。我们采用了一种跨诊断的恢复定义,包括体重和与饮食相关的精神病理学的正常化。
EOT 时达到预期体重的 95.2%是青少年厌食症(AN)恢复的最佳预测因子。对于 AN 成人患者,体重恢复(BMI>19)的最有效预测因子是体重增加到理想体重的 85.8%以上。此外,对于 AN 成人患者,心理恢复的最有效预测因子是饮食失调检查(EDE)体重担忧评分低于 1.8。神经性贪食症(BN)成人患者恢复的最佳预测因子是补偿行为的频率低于每月两次。对于 BN 青少年患者,从 EOT 到 EOT 期间停止呕吐和 EDE 限制评分减少 3.4 以上是恢复的良好预测因子。对于暴食障碍成人患者,将全球 EDE 评分降低到正常范围内(<1.58)是恢复的最佳预测因子。
EOT 反应与恢复之间的关系仍研究不足。采用跨诊断的恢复定义,在所有饮食失调诊断组中都没有确定统一的预测因子。