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[一名44岁菲律宾女性的上腹部疼痛和发热发作]

[Upper abdominal pain and febrile episodes in a 44-year-old Filipino woman].

作者信息

Deimel A, Sturm J, Vielfort T, Zöpf T

机构信息

ZEuS (Zentrum für Endoskopie und Ultraschall), Medizinische Klinik I, ViDiA Christliche Kliniken Karlsruhe, Diakonissenstr. 28, 76199, Karlsruhe, Deutschland.

Klinik für Allgemein‑, Viszeral- und Gefäßchirurgie, ViDiA Christliche Kliniken Karlsruhe, Diakonissenstraße 28, 79166 Karlsruhe, Deutschland.

出版信息

Internist (Berl). 2018 Mar;59(3):276-281. doi: 10.1007/s00108-017-0320-2.

DOI:10.1007/s00108-017-0320-2
PMID:28939930
Abstract

A 44-year-old Filipino woman presented with abdominal pain and fever. Clinical examination and blood tests revealed no pathological results; however, (cross-sectional) imaging showed saccular cystic bile duct dilatation in the right liver with solid intraductal masses. Due to the clinical presentation the patient was admitted for surgical intervention with the diagnosis of Caroli disease. During the surgical procedure histopathology showed an intraductal papillary neoplasm of the bile duct (IPNB). The planned segmentetomy was extended to hemihepatectomy. IPNB is a rare entity of premalignant lesions of the bile duct system first recognized by the World Health Organization in 2010.

摘要

一名44岁的菲律宾女性因腹痛和发热前来就诊。临床检查和血液检测未发现病理结果;然而,(横断面)影像学检查显示右肝内囊状胆管扩张,伴有胆管内实性肿块。鉴于临床表现,患者因卡罗里病的诊断入院接受手术干预。手术过程中,组织病理学显示为胆管内乳头状肿瘤(IPNB)。原计划的节段性肝切除术扩大为半肝切除术。IPNB是胆管系统癌前病变的一种罕见类型,于2010年首次被世界卫生组织认可。

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本文引用的文献

1
Updates on Precancerous Lesions of the Biliary Tract: Biliary Precancerous Lesion.胆道癌前病变的最新进展:胆道癌前病变
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2
Comparative clinicopathological study of biliary intraductal papillary neoplasms and papillary cholangiocarcinomas.胆管内乳头状肿瘤与乳头状胆管癌的临床病理对照研究
Histopathology. 2016 Dec;69(6):950-961. doi: 10.1111/his.13037. Epub 2016 Sep 23.
3
Systematic Review and Meta-analysis of Current Experience in Treating IPNB: Clinical and Pathological Correlates.
肝内胆管乳头状瘤病当前治疗经验的系统评价与荟萃分析:临床与病理相关性
Ann Surg. 2016 Apr;263(4):656-63. doi: 10.1097/SLA.0000000000001426.
4
Caroli's disease misdiagnosed as intraductal papillary neoplasm of the bile duct.被误诊为胆管内乳头状瘤的卡罗利病
Clin Mol Hepatol. 2015 Jun;21(2):175-9. doi: 10.3350/cmh.2015.21.2.175. Epub 2015 Jun 26.
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Intraductal papillary neoplasms of the bile duct.胆管内乳头状肿瘤
Int J Hepatol. 2014;2014:459091. doi: 10.1155/2014/459091. Epub 2014 May 18.
6
Histological Characterization of Biliary Intraepithelial Neoplasia with respect to Pancreatic Intraepithelial Neoplasia.胆管上皮内瘤变相对于胰腺上皮内瘤变的组织学特征
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8
Intraductal papillary neoplasm of the bile duct: a biliary equivalent to intraductal papillary mucinous neoplasm of the pancreas?胆管内乳头状肿瘤:胆管内乳头状黏液性肿瘤相当于胰腺内的肿瘤吗?
Hepatology. 2012 Oct;56(4):1352-60. doi: 10.1002/hep.25786. Epub 2012 Aug 27.
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Cancer. 2004 Feb 15;100(4):783-93. doi: 10.1002/cncr.20031.
10
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Int Abstr Surg. 1959 Jan;108(1):1-30.