Unick Jessica L, Gaussoin Sarah A, Hill James O, Jakicic John M, Bond Dale S, Hellgren Margareta, Johnson Karen C, Peters Anne L, Coday Mace, Kitzman Dalane W, Bossart Suzette, Wing Rena R
Weight Control and Diabetes Research Center, The Miriam Hospital, Providence, Rhode Island, USA.
Department of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA.
Obesity (Silver Spring). 2017 Nov;25(11):1903-1909. doi: 10.1002/oby.21971. Epub 2017 Sep 20.
To examine the relationship between objectively assessed moderate-to-vigorous intensity physical activity (MVPA) and 4-year weight loss (WL) and WL maintenance among individuals with diabetes enrolled in the Look AHEAD trial.
MVPA was measured in a subgroup of lifestyle intervention participants with accelerometry data at baseline and at 1 and 4 years (n = 553; age: 59.7 ± 6.8 y; BMI: 35.5 ± 5.9 kg/m ). Minutes per week of bout-related MVPA were calculated (≥ 3 metabolic equivalents, ≥ 10-min bouts), and adherence to the national physical activity (PA) recommendation for WL maintenance (≥ 250 min/wk) was assessed.
Independent of 1-year WL, 4-year MVPA (β = -0.003, SE = 0.002, P = 0.006), but not 1-year MVPA (β = 0.0001, SE = 0.001, P = 0.50), was significantly associated with 4-year WL. Compared with "nonmaintainers" (≥ 10% WL at year 1, but < 10% at year 4; n = 132), WL maintainers (≥ 10% WL at years 1 and 4; n = 103) had higher MVPA at year 1 (253.4 ± 251.8 vs. 163.9 ± 158.2 min/wk, P = 0.002) and year 4 (155.3 ± 180.6 vs. 111.4 ± 154.5 min/wk, P = 0.046). Although 38.8% and 22.3% of WL maintainers engaged in ≥ 250 min/wk at years 1 and 4, respectively, many engaged in < 150 min/wk (year 1: 41%, year 4: 61%).
Higher weekly MVPA is associated with greater long-term WL and weight maintenance; however, many individuals are able to maintain ≥ 10% WL while engaging in little MVPA.
在参加“展望未来”(Look AHEAD)试验的糖尿病患者中,研究客观评估的中等到剧烈强度身体活动(MVPA)与4年体重减轻(WL)及体重维持之间的关系。
在生活方式干预参与者的一个亚组中测量MVPA,这些参与者在基线、1年和4年时均有加速度计数据(n = 553;年龄:59.7±6.8岁;体重指数:35.5±5.9kg/m²)。计算每周与发作相关的MVPA分钟数(≥3代谢当量,≥10分钟发作),并评估对国家身体活动(PA)维持体重建议(≥250分钟/周)的依从性。
不考虑1年体重减轻情况,4年MVPA(β = -0.003,标准误 = 0.002,P = 0.006)与4年体重减轻显著相关,而1年MVPA(β = 0.0001,标准误 = 0.001,P = 0.50)与4年体重减轻无显著关联。与“体重未维持者”(第1年体重减轻≥10%,但第4年<10%;n = 132)相比,体重维持者(第1年和第4年体重减轻均≥10%;n = 103)在第1年(253.4±251.8 vs. 163.9±158.2分钟/周,P = 0.002)和第4年(155.3±180.6 vs. 111.4±154.5分钟/周,P = 0.046)的MVPA更高。尽管分别有38.8%和22.3%的体重维持者在第1年和第4年每周进行≥250分钟的MVPA,但许多人每周进行的MVPA<150分钟(第1年:41%;第4年:61%)。
每周较高的MVPA与更大程度的长期体重减轻和体重维持相关;然而,许多人在很少进行MVPA的情况下仍能维持≥10%的体重减轻。