Tyldesley W R
Br J Oral Surg. 1979 Jul;17(1):1-9. doi: 10.1016/0007-117x(79)90001-5.
It has become widely recognised that oral lesions may occur in patients with Crohn's disease of the lower gastro-intestinal tract. Patients have also been described with oral lesions of this kind unassociated with gut lesions. The purpose of this paper is to describe the clinical presentation of seven such patients. The resemblance of their lesions to those of the condition known as chronic granulomatous cheilitis is pointed out. The association between the oral lesions and those of the lower gut is discussed and it is reported that in one patient acute toxic dilation of the colon due to Crohn's disease followed a period in which oral lesions only were recognised.
人们已经普遍认识到,患有下消化道克罗恩病的患者可能会出现口腔病变。也有患者被描述患有此类口腔病变但与肠道病变无关。本文的目的是描述7例这类患者的临床表现。指出了他们的病变与称为慢性肉芽肿性唇炎的病症的病变相似之处。讨论了口腔病变与下消化道病变之间的关联,并报告了1例患者在仅发现口腔病变一段时间后,因克罗恩病出现了结肠急性中毒性扩张。