Scully C, Cochran K M, Russell R I, Ferguson M M, Ghouri M A, Lee F D, MacDonald D G, McIntyre P B
Gut. 1982 Mar;23(3):198-201. doi: 10.1136/gut.23.3.198.
Nineteen patients with clinical evidence of oral Crohn's disease but no intestinal symptoms were studied. Oral lesions in all patients were shown histologically to have lymphoedema with or without chronic granulomas consistent with Crohn's disease. Seven patients (37%) had demonstrable intestinal disease on rectal biopsy and four of these had abnormal bowel radiology. All seven had evidence of nutritional deficiency. Patients with clinical features suggesting oral Crohn's disease may have evidence of Crohn's disease in the intestine, although this may not be clinically apparent.
对19例有口腔克罗恩病临床证据但无肠道症状的患者进行了研究。所有患者的口腔病变经组织学检查显示有淋巴水肿，伴有或不伴有与克罗恩病相符的慢性肉芽肿。7例患者（37%）直肠活检显示有肠道疾病，其中4例肠道放射学检查异常。所有7例均有营养缺乏的证据。有提示口腔克罗恩病临床特征的患者可能在肠道有克罗恩病的证据，尽管这在临床上可能不明显。
