儿童肥厚型心肌病
Hypertrophic cardiomyopathy in children.
作者信息
Arghami Arman, Dearani Joseph A, Said Sameh M, O'Leary Patrick W, Schaff Hartzell V
机构信息
Department of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Division of Pediatric Cardiology, Mayo Clinic, Rochester, Minnesota, USA.
出版信息
Ann Cardiothorac Surg. 2017 Jul;6(4):376-385. doi: 10.21037/acs.2017.07.04.
Abstract
Hypertrophic cardiomyopathy (HCM) occurs in 1 of 500 adults and is considered to be one of the most common causes of death in young people under 35 years of age. Children with HCM are usually asymptomatic and the overall annual mortality beyond the first year of life is 1%. Septal myectomy is safe and effective in children with obstructive HCM and published data shows improved late survival compared to untreated HCM. Patient selection and surgical expertise remain critical components to ensuring successful outcomes of septal myectomy, particularly when considering prophylactic myectomy in a seemingly asymptomatic patient.
摘要
肥厚型心肌病（HCM）在每500名成年人中就有1例发病，被认为是35岁以下年轻人最常见的死亡原因之一。患有HCM的儿童通常没有症状，1岁以后的总体年死亡率为1%。对于梗阻性HCM患儿，室间隔肌切除术是安全有效的，已发表的数据表明，与未经治疗的HCM相比，晚期生存率有所提高。患者选择和手术专业知识仍然是确保室间隔肌切除术成功结果的关键因素，特别是在考虑对看似无症状的患者进行预防性肌切除术时。
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