Ra Song-Gyu, Miyazaki Teruo, Kojima Ryo, Komine Shoichi, Ishikura Keisuke, Kawanaka Kentaro, Honda Akira, Matsuzaki Yasushi, Ohmori Hajime
Faculty of Sports and Health Sciences, Fukuoka University, Fukuoka, Japan.
Joint Research Center, Tokyo Medical University, Ibaraki Medical Center, Ibaraki, Japan.
J Sports Med Phys Fitness. 2018 Nov;58(11):1582-1591. doi: 10.23736/S0022-4707.17.07638-1. Epub 2017 Sep 22.
The aim of the present study was to compare the effects of branched-chain amino acid (BCAA) supplementation taken before or after exercise on delayed onset muscle soreness (DOMS) and exercise-induced muscle damage (EIMD).
Fifteen young men (aged 21.5±0.4 years) were given either BCAA (9.6 g·day-1) or placebo before and after exercise (and for 3 days prior to and following the exercise day) in three independent groups: the control group (placebo before and after exercise), the PRE group (BCAA before exercise and placebo after exercise), and the POST group (placebo before exercise and BCAA after exercise). Participants performed 30 repetitions of eccentric exercise with the non-dominant arm. DOMS, upper arm circumference (CIR), elbow range of motion (ROM), serum creatine kinase (CK), lactate dehydrogenase (LDH), and aldolase, BCAA, and β-hydroxy-β-methylbutyrate (3HMB) were measured immediately before and after the exercise and on the following 4 days.
Serum BCAA and 3HMB concentrations increased significantly in the PRE group immediately after the exercise, recovering to baseline over the following days. In the days following the exercise day, DOMS, CIR, and ROM were significantly improved in the PRE group compared to the control group, with weaker effects in the POST group. Serum activities of CK, LDH, and aldolase in the days following the exercise day were significantly suppressed in the PRE group compared to control group.
The present study confirmed that repeated BCAA supplementation before exercise had a more beneficial effect in attenuating DOMS and EIMD induced by eccentric exercise than repeated supplementation after exercise.
本研究的目的是比较运动前或运动后补充支链氨基酸（BCAA）对延迟性肌肉酸痛（DOMS）和运动诱导的肌肉损伤（EIMD）的影响。
15名年轻男性（年龄21.5±0.4岁）被分为三个独立组，在运动前和运动后（以及运动日之前和之后的3天）分别给予BCAA（9.6 g·天-1）或安慰剂：对照组（运动前和运动后均为安慰剂）、PRE组（运动前给予BCAA，运动后给予安慰剂）和POST组（运动前给予安慰剂，运动后给予BCAA）。参与者用非优势手臂进行30次离心运动。在运动前和运动后以及随后的4天测量DOMS、上臂围（CIR）、肘部活动范围（ROM）、血清肌酸激酶（CK）、乳酸脱氢酶（LDH）、醛缩酶、BCAA和β-羟基-β-甲基丁酸（3HMB）。
运动后PRE组血清BCAA和3HMB浓度立即显著升高，在随后几天恢复到基线水平。在运动日后的几天里，与对照组相比，PRE组的DOMS、CIR和ROM有显著改善，POST组的效果较弱。与对照组相比，运动日后PRE组血清CK、LDH和醛缩酶的活性在运动日后的几天里受到显著抑制。
本研究证实，运动前重复补充BCAA在减轻离心运动诱导的DOMS和EIMD方面比运动后重复补充更有益。
