美国移民和海关执法局被拘留者对水痘的血清易感性
Serological Susceptibility to Varicella Among U.S. Immigration and Customs Enforcement Detainees.
作者信息
Varan Aiden K, Lederman Edith R, Stous Shanon S, Elson Diana, Freiman Jennifer L, Marin Mona, Lopez Adriana S, Stauffer William M, Joseph Rachael H, Waterman Stephen H
机构信息
1 CDC/CSTE Applied Epidemiology Fellowship Program, Atlanta, GA, USA.
2 Division of Global Migration and Quarantine, Centers for Disease Control and Prevention, San Diego, CA, USA.
出版信息
J Correct Health Care. 2018 Jan;24(1):84-95. doi: 10.1177/1078345817727287. Epub 2017 Sep 25.
U.S. Immigration and Customs Enforcement (ICE) is responsible for detaining unauthorized aliens during immigration proceedings. During 2014 to 2015, adult ICE detainees at a California facility were invited to complete a survey concerning self-reported varicella history and risk factors. Participants underwent serological testing for varicella-zoster virus (VZV) IgG; susceptible individuals were offered varicella vaccination. Among 400 detainees with available serology results, 48 (12%) were susceptible to varicella. Self-reported varicella history was negatively associated with susceptibility (adjusted odds ratio = 0.16; 95% confidence interval [0.07, 0.35]). Among 196 detainees reporting a positive history, 95% had VZV IgG levels suggestive of varicella immunity. Among 44 susceptible detainees offered vaccination, 86% accepted. Given relatively high varicella susceptibility, targeted screening and vaccination among ICE detainees lacking a positive history might reduce varicella transmission risks.
美国移民和海关执法局（ICE）负责在移民程序中拘留未经授权的外国人。在2014年至2015年期间，加利福尼亚州一家设施中的成年ICE被拘留者受邀完成一项关于自我报告的水痘病史和风险因素的调查。参与者接受了水痘-带状疱疹病毒（VZV）IgG的血清学检测；对易感个体提供了水痘疫苗接种。在400名有可用血清学结果的被拘留者中，48人（12%）对水痘易感。自我报告的水痘病史与易感性呈负相关（调整后的优势比=0.16；95%置信区间[0.07,0.35]）。在196名报告有阳性病史的被拘留者中，95%的人VZV IgG水平表明具有水痘免疫力。在44名被提供疫苗接种的易感被拘留者中，86%接受了接种。鉴于水痘易感性相对较高，对没有阳性病史的ICE被拘留者进行有针对性的筛查和疫苗接种可能会降低水痘传播风险。
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