Department of Chemistry, Massachusetts Institute of Technology , 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
Acc Chem Res. 2017 Mar 21;50(3):577-579. doi: 10.1021/acs.accounts.6b00561.
Metal ions play critical roles in neurotransmission, memory formation, and sensory perception. Understanding the molecular details of these processes is the Holy Grail of metalloneurochemistry. Here we describe five challenges for collaborative teams of chemists, biologists, and neuroscientists to help make this dream a reality.
金属离子在神经传递、记忆形成和感官感知中发挥着关键作用。了解这些过程的分子细节是金属神经化学的圣杯。在这里,我们描述了化学家、生物学家和神经科学家合作团队面临的五个挑战,以帮助实现这一梦想。