Department of Chemistry, Department of Molecular and Cell Biology, Howard Hughes Medical Institute, and Helen Wills Neuroscience Institute, University of California , Berkeley, California 94720, United States.
Chemical Sciences Division, Lawrence Berkeley National Laboratory , Berkeley, California 94720, United States.
Acc Chem Res. 2017 Mar 21;50(3):535-538. doi: 10.1021/acs.accounts.6b00531.
Identifying what elements are required for neural activity as potential path toward consciousness, which represents life with the state or quality of awareness, is a "Holy Grail" of chemistry. As life itself arises from coordinated interactions between elements across the periodic table, the majority of which are metals, new approaches for analysis, binding, and control of these primary chemical entities can help enrich our understanding of inorganic chemistry in living systems in a context that is both universal and personal.
确定神经活动的要素是什么，这些要素可能是通向意识的途径，而意识代表着具有觉察状态或质量的生命，这是化学的“圣杯”。由于生命本身源于元素在周期表上的协调相互作用，其中大多数元素是金属，因此，分析、结合和控制这些主要化学实体的新方法可以帮助我们在普遍和个人的背景下丰富对生命系统中无机化学的理解。
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