Department of Ultrasound, Peking University First Hospital, Beijing 100034, China.
Department of Pathology, Peking University First Hospital, Beijing 100034, China.
Cancer Biomark. 2017 Sep 7;20(3):235-240. doi: 10.3233/CBM-160544.
This study aims to evaluate the diagnostic value of ultrasound in thyroid Hürthle cell tumors.
A retrospective analysis was carried out on 27 patients with thyroid Hürthle cell tumors, in terms of the size, shape, boundary, echo, aspect ratio, cystic degeneration, calcification, peripheral halo sign and blood supply of the tumor, through surgical pathological validation. Then, these were compared with postoperative pathological results.
The maximum diameter of the thyroid Hürthle cell tumors is between 0.6 cm and 4.6 cm. It had an oval nodule with clear boundaries, an aspect ratio > 1, and peripheral low-echo halos. Furthermore, 29.6% of tumors have even low-echo nodules without cystic changes, 48.1% and 22.1% have even medium or medium-low mixed echo nodules, and 44.4% have cystic changes in varying degrees. One nodule appeared with "micro-calcification", but pathological results confirmed that it was local collagen. Color Doppler blood flow imaging revealed that 88.8% of the nodules were surrounded with blood flow, filled with rich blood inside, and only 12.2% of the nodules had a little blood inside.
Thyroid Hürthle cell tumors have nodules with even or uneven echoes on the background of the normal echoes of the thyroid, with an aspect ratio of > 1, clear boundaries and peripheral acoustic halos. Cystic changes, colloid crystallization and fibrosis can be seen inside in varying degrees. Ultrasonography has no significant value for the differential diagnosis of benign and malignant Hürthle cell tumors.
本研究旨在评估超声在甲状腺 Hurthle 细胞肿瘤中的诊断价值。
对 27 例经手术病理证实的甲状腺 Hurthle 细胞肿瘤患者的肿瘤大小、形态、边界、回声、纵横比、囊性变、钙化、周边晕环征及血供等超声表现进行回顾性分析,并与术后病理结果进行比较。
甲状腺 Hurthle 细胞肿瘤最大直径 0.6~4.6cm,多为类圆形结节,边界清晰,纵横比>1,周边低回声晕环。瘤内回声不均匀,29.6%瘤内为均匀低回声结节,无囊性变,48.1%和 22.1%瘤内为均匀中等或中等偏低回声结节,44.4%瘤内可见不同程度囊性变。1 个结节内出现“微钙化”,但病理证实为局部胶原。彩色多普勒血流显像显示 88.8%的结节周边血流环绕,内部血流丰富,仅 12.2%的结节内部血流稍丰富。
甲状腺 Hurthle 细胞肿瘤的结节在甲状腺正常回声背景上呈不均匀或均匀回声,纵横比>1,边界清晰,周边有声晕。瘤内可出现不同程度的囊性变、胶体结晶及纤维化,超声对 Hurthle 细胞肿瘤良恶性的鉴别诊断价值不大。