Brezin F, Wiedemann A, Feillet F
Service de médecine infantile I, CHU Nancy-Brabois, rue du Morvan, 54500 Vandœuvre-Lès-Nancy, France.
Service de médecine infantile I, CHU Nancy-Brabois, rue du Morvan, 54500 Vandœuvre-Lès-Nancy, France; Centre de référence des maladies héréditaire du métabolisme, CHU Nancy-Brabois, rue du Morvan, 54500 Vandœuvre-Lès-Nancy, France.
Arch Pediatr. 2017 Nov;24(11):1129-1136. doi: 10.1016/j.arcped.2017.08.010. Epub 2017 Sep 22.
Cyclic vomiting syndrome (CVS) is a misrecognized and probably underdiagnosed disease that can affect up to 1.9% of the pediatric population and can occupy 15% of these children's time. It is characterized by acute attacks of vomiting, occurring with such a strict frequency that some parents can predict the date of their child's next attack. The pathophysiology of CVS is unclear, although the literature recognizes a common origin with migraine headaches, which has the same acute and prophylactic treatment. CVS is now included in the larger group of diseases called "episodic symptoms related to migraine" previously known as "childhood periodic syndromes." To distinguish between real CVS and other differential diagnoses can challenge the clinician. Additional investigations must be considered in accordance with the clinical presentation. Appropriate management of CVS should lead to an improvement in quality of life and school attendance.
周期性呕吐综合征(CVS)是一种常被误诊且可能诊断不足的疾病,影响着高达1.9%的儿童群体,且占据这些儿童15%的时间。其特征为急性呕吐发作,发作频率极为规律,以至于一些家长能够预测孩子下次发作的日期。尽管文献认为CVS与偏头痛有共同起源,且治疗方式包括急性发作期治疗和预防性治疗均相同,但CVS的病理生理学仍不清楚。CVS现被纳入更大的一组疾病,即“与偏头痛相关的发作性症状”,以前称为“儿童周期性综合征”。区分真正的CVS和其他鉴别诊断可能会给临床医生带来挑战。必须根据临床表现考虑进行进一步检查。对CVS进行适当管理应能改善生活质量和上学出勤率。