Song Jian, Wang Hong-Li, Ma Xiao-Sheng, Xia Xin-Lei, Lu Fei-Zhou, Zheng Chao-Jun, Jiang Jian-Yuan
Department of Orthopaedics, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Oncotarget. 2017 Jun 27;8(36):60558-60567. doi: 10.18632/oncotarget.18652. eCollection 2017 Sep 1.
To explore value of different radiographic indexes in the diagnosis of discogenic low back pain (LBP). A total number of 120 cases (60 patients diagnosed with discogenic LBP and 60 healthy people) were retrospectively analysed to identify factors in the diagnosis of discogenic LBP by using univariate and multivariate analyses. A receiver operating characteristic (ROC) curve was drew to show the predictive accuracy of the finally enrolled factors. Among all the included patients, 60 were strictly admitted in the discogenic LBP group while the other 60 were enrolled in the control group. Five results shows significant differences between discogenic LBP and control groups, including Cobb angle, lumbar stability, height of the disc, Modic change and High intense zone (HIZ) based on the results of univariate analysis; lumbar stability, Modic change and HIZ show high value in the diagnosis of lumbar discogenic pain based on the multivariate logistic analysis. The ROC curve shows that good diagnostic accuracy was obtained from the enrolled diagnostic factors including lumbar stability (Angular motion, more than 14.35°), Modic change and HIZ.
探讨不同影像学指标在诊断椎间盘源性下腰痛(LBP)中的价值。回顾性分析120例患者(60例诊断为椎间盘源性LBP的患者和60例健康人),通过单因素和多因素分析确定椎间盘源性LBP诊断中的因素。绘制受试者工作特征(ROC)曲线以显示最终纳入因素的预测准确性。在所有纳入患者中,60例被严格纳入椎间盘源性LBP组,另外60例纳入对照组。单因素分析结果显示,Cobb角、腰椎稳定性、椎间盘高度、Modic改变和高信号区(HIZ)这五项结果在椎间盘源性LBP组和对照组之间存在显著差异;基于多因素逻辑分析,腰椎稳定性、Modic改变和HIZ在腰椎间盘源性疼痛的诊断中显示出较高价值。ROC曲线显示,纳入的诊断因素包括腰椎稳定性(角运动,大于14.35°)、Modic改变和HIZ具有良好的诊断准确性。