Wang Zi-Xuan, Hu You-Gu, Chen Xiang-Min
Department of Interventional Radiology, Qingdao Municipal Hospital, Qingdao University, Qingdao 266000, China.
Zhonghua Yi Xue Za Zhi. 2008 Sep 16;88(35):2478-81.
To investigate the prevalence of high-intensity zone (HIZ) and the correlation between HIZ and low back pain (LBP).
The data of 1000 unselected cases, 566 males and 434 females, aged 49.49 (12 - 86), who underwent lumbar MRI were analyzed to examine the prevalence of HIZ. 200 of the 1000 cases with HIZ which had complete clinical history records, 112 males and 88 females, aged 52.29 (18 - 86), were divided into LBP (n = 115) and non-LBP series (n = 85). CT discography (CTD) was performed in 16 discs in 11 cases with HIZ and the correlation between the modified Dallas' discogram scale and pain reproduction in provocation discography was explored.
HIZ located in posterior annulus fibrosus (AF) was shown in 378 discs in 317 cases, most located in L4/5 and L5/S1 (74.8%) and the location in left side (153 HIZs) was more common than that in right side (94 HIZs). HIZs were shown in superior region (15.4%), middle region (28.8%), as well as inferior region (55.8%) in sagittal plane. 115 of the 200 cases with HIZ who had complete clinical history records (57.5%) were symptomatic and 85 cases (42.5%) were asymptomatic. According to the modified Dallas' discogram scale, LBP could be provoked in 8 of the 9 patients with grade IV and could not be provoked in 6 of the 7 patients with the grade III.
Whether HIZ is accompanied with LBP is related to the degree of disc degeneration. When CTD showed the degree of modified Dallas' grade IV and over most of the patients will show LBP. HIZ only indicates the possibility of discogenic LBP and can not replace provocation discography.
探讨高强度区(HIZ)的发生率以及HIZ与腰痛(LBP)之间的相关性。
对1000例未经挑选、年龄为49.49岁(12 - 86岁)的患者(男性566例,女性434例)的腰椎MRI数据进行分析,以检查HIZ的发生率。在1000例有HIZ且有完整临床病史记录的患者中,选取200例(男性112例,女性88例,年龄52.29岁,18 - 86岁),分为腰痛组(n = 115)和无腰痛组(n = 85)。对11例有HIZ的患者的16个椎间盘进行了CT椎间盘造影(CTD),并探讨了改良的达拉斯椎间盘造影分级与激发性椎间盘造影中疼痛再现之间的相关性。
317例患者的378个椎间盘显示HIZ位于纤维环后部(AF),大多数位于L4/5和L5/S1(74.8%),左侧(153个HIZ)的位置比右侧(94个HIZ)更常见。矢状面显示HIZ位于上区(15.4%)、中区(28.8%)以及下区(55.8%)。在200例有HIZ且有完整临床病史记录的患者中,115例(57.5%)有症状,85例(42.5%)无症状。根据改良的达拉斯椎间盘造影分级,9例IV级患者中有8例可诱发腰痛,7例III级患者中有6例不能诱发腰痛。
HIZ是否伴有LBP与椎间盘退变程度有关。当CTD显示改良的达拉斯分级为IV级及以上时,大多数患者会出现LBP。HIZ仅提示椎间盘源性LBP的可能性,不能替代激发性椎间盘造影。