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既往患有妊娠期糖尿病女性的特定代谢特征:脂肪组织的重要性

Specific metabolic characteristics of women with former gestational diabetes: the importance of adipose tissue.

作者信息

Vejrazkova D, Vankova M, Lukasova P, Vcelak J, Cirmanova V, Haluzik M, Bendlova B

机构信息

Institute of Endocrinology, Prague, Czech Republic.

出版信息

Physiol Res. 2017 Sep 26;66(Suppl 3):S349-S356. doi: 10.33549/physiolres.933726.

DOI:10.33549/physiolres.933726
PMID:28948819
Abstract

Women with a positive history of gestational diabetes mellitus (GDM) face a higher risk of developing type 2 diabetes mellitus (T2DM) and metabolic syndrome later in life. The higher risk of these metabolic complications is closely associated with adipose tissue. In this review, the importance of adipose tissue is discussed in relation to GDM, focusing on both the quantity of fat deposits and the metabolic activity of adipose tissue in particular periods of life: neonatal age, childhood, adolescence, and pregnancy followed by nursing. Preventive measures based on body composition and lifestyle habits with special attention to the beneficial effects of breastfeeding are also discussed.

摘要

有妊娠期糖尿病(GDM)病史的女性在日后患2型糖尿病(T2DM)和代谢综合征的风险更高。这些代谢并发症的较高风险与脂肪组织密切相关。在本综述中,将讨论脂肪组织在GDM中的重要性,重点关注脂肪沉积量以及在生命特定时期(新生儿期、儿童期、青春期、孕期及产后哺乳期)脂肪组织的代谢活性。还将讨论基于身体成分和生活方式习惯的预防措施,特别关注母乳喂养的有益效果。

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