[科特迪瓦的HIV-1、HIV-2逆转录病毒感染及艾滋病相关综合征]

[Retroviral infections by HIV-1, HIV-2 and AIDS-related complex in the Ivory Coast].

作者信息

Ouattara A, Rey M A, Brun-Vésinet F, Kindbeiter K, de Thé G

机构信息

Laboratoire d'Epidémiologie et Immunovirologie des Tumeurs, Faculté de Médecine Alexis-Carrel, Lyon.

出版信息

C R Acad Sci III. 1988;306(2):47-50.

PMID:2894887

Abstract

The study of 500 blood donors, of 23 prostitutes, 22 confirmed AIDS cases and 19 ARC patients in Abidjan showed that HIV-2 prevalence in blood donors (3.4%) was somewhat higher than that of HIV-1 (2.4%). Furthermore HIV-2 alone was found associated with 14% of AIDS cases and 21% of ARC, while HIV-1 was associated with 32% of the cases. Antibodies to HIV-1 and HIV-2 were found in 54% of AIDS and ARC cases, as well as in 48% of the prostitutes sera. These preliminary results suggest that HIV-2 is pathogenic, being causally involved in some AIDS cases and does not protect from HIV-1 pathogenic potential.

摘要

在阿比让对500名献血者、23名妓女、22例确诊艾滋病病例和19例艾滋病相关综合征（ARC）患者的研究表明，献血者中HIV-2的流行率（3.4%）略高于HIV-1（2.4%）。此外，仅发现HIV-2与14%的艾滋病病例和21%的ARC相关，而HIV-1与32%的病例相关。在54%的艾滋病和ARC病例以及48%的妓女血清中发现了针对HIV-1和HIV-2的抗体。这些初步结果表明，HIV-2具有致病性，在某些艾滋病病例中起因果作用，并且不能预防HIV-1的致病潜力。