Vasin M V, Gavriliuk D N
Farmakol Toksikol. 1979 Jul-Aug;42(4):376-8.
The effect of mexamin (5 and 10 mg/kg) on the vascular tone of thoracic and abdominal cavity vessels and pelvic limbs was investigated by angiography in experiments on 19 mongrel dogs under nembutal anesthesia (30 mg/kg). 5-7 minutes after intramuscular administration of the drug there was a constriction of the aorta, of the hepatic, splenic, cranial mesenteric, internal and external iliac, branched femoral and tibial arteries by about 15-40% as compared to the initial diameter. Mexamin exerted no substantial vasoconstrictive action on the segmental (intercostal, lumbar, phrenoabdominal) and renal arteries.
在19只经戊巴比妥（30mg/kg）麻醉的杂种犬身上进行实验，通过血管造影术研究了美沙明（5和10mg/kg）对胸腹腔血管及盆腔肢体血管张力的影响。肌肉注射该药5 - 7分钟后，与初始直径相比，主动脉、肝动脉、脾动脉、肠系膜前动脉、髂内和髂外动脉、股动脉分支和胫动脉收缩约15 - 40%。美沙明对节段性（肋间、腰、膈腹）动脉和肾动脉没有显著的血管收缩作用。
