含抗菌剂生物敷料的抗菌特性

Antimicrobial properties of antiseptic-impregnated biological dressings.

作者信息

Kearney J N, Arain T, Holland K T

机构信息

Yorkshire Regional Tissue Bank, Pinderfields General Hospital, Wakefield, UK.

出版信息

J Hosp Infect. 1988 Jan;11(1):68-76. doi: 10.1016/0195-6701(88)90041-2.

DOI:10.1016/0195-6701(88)90041-2

PMID:2895140

Abstract

Three antiseptics--chlorhexidine acetate, silver nitrate and povidone-iodine--were incorporated into biological dressings (human skin and amnio-chorion) and evaluated in vitro against disparate micro-organisms. Results indicated that antimicrobial levels of chlorhexidine and silver were released from the dressings over a clinically relevant time period, whereas povidone-iodine was ineffective. Chlorhexidine dressings demonstrated broad-spectrum activity, whereas silver dressings were most effective against Pseudomonas aeruginosa.

摘要

将三种防腐剂——醋酸氯己定、硝酸银和聚维酮碘——添加到生物敷料（人皮和羊膜绒毛膜）中，并在体外针对不同微生物进行评估。结果表明，在临床相关时间段内，敷料释放出氯己定和银的抗菌成分，而聚维酮碘则无效。氯己定敷料显示出广谱活性，而银敷料对铜绿假单胞菌最有效。