Carson J L, Poses R M, Spence R K, Bonavita G
Department of Medicine, University of Medicine and Dentistry of New Jersey/Robert Wood Johnson Medical School, New Brunswick.
Lancet. 1988 Apr 2;1(8588):727-9. doi: 10.1016/s0140-6736(88)91536-x.
In a case-control study of 125 surgical patients who declined blood transfusions for religious reasons operative mortality was inversely related to the preoperative haemoglobin level, rising from 7.1% for patients with levels above 10 g/dl to 61.5% for those with levels below 6 g/dl. Mortality rates were also related to blood loss during surgery, rising from 8% for patients who lost less than 500 ml to 42.9% for those who lost more than 2000 ml. Both preoperative haemoglobin level and operative blood loss should be considered in assessing the need for preoperative transfusion. In our study no patient with a haemoglobin level above 8 g/dl and operative blood loss below 500 ml died.
在一项针对125名因宗教原因拒绝输血的外科手术患者的病例对照研究中，手术死亡率与术前血红蛋白水平呈负相关，血红蛋白水平高于10 g/dl的患者手术死亡率为7.1%，而低于6 g/dl的患者手术死亡率则升至61.5%。死亡率也与手术期间的失血量有关，失血量少于500毫升的患者死亡率为8%，而失血量超过2000毫升的患者死亡率为42.9%。在评估术前输血需求时，应同时考虑术前血红蛋白水平和手术失血量。在我们的研究中，血红蛋白水平高于8 g/dl且手术失血量低于500毫升的患者无一死亡。
