Commey J O, Dekyem P
Department of Child Health, University of Ghana Medical School, Accra, Ghana.
West Afr J Med. 1995 Apr-Jun;14(2):101-4.
Severe anaemia has remained a major cause of morbidity and mortality in children of Southern Ghana since the early 1960s. 71.1% of 15450 children attending the Korle Bu Teaching Hospital, Accra referred to the laboratory for haematological studies had haemoglobin (HB) levels below 11.0 Gm/dl while 27.7% of anaemic patients had Hb levels below 7.0 gm/dl. Indeed, 71.1% of children with severe anaemia had Hb levels below 5.0 gm/dl, thus requiring urgent blood transfusion. Though the Department of Child Health alone utilised 32.2% of total blood processed by the National Blood Transfusion Service at Korle Bu, as many as 259 (58.1%) of the 554 deaths in the emergency rooms per annum in children beyond the neonatal period were related to severe anaemia. Iron deficiency was the commonest cause of anaemia and contributed further to the anaemias of sickle cell disease and protein--energy malnutrition. In the light of the significant decline in the prevalence of childhood anaemia in the developed world following improved counseling in nutrition, fortification of foods with iron, and iron supplementation to infants and school children, and the documented attendant improvement in growth velocity and intellectual performance we support the planned national anaemia survey and recommend for early consideration iron supplementation to older infants and pre-school children at risk.
自20世纪60年代初以来,重度贫血一直是加纳南部儿童发病和死亡的主要原因。在阿克拉科勒布教学医院就诊并被送往实验室进行血液学研究的15450名儿童中,71.1%的儿童血红蛋白(HB)水平低于11.0克/分升,而27.7%的贫血患者血红蛋白水平低于7.0克/分升。事实上,71.1%的重度贫血儿童血红蛋白水平低于5.0克/分升,因此需要紧急输血。尽管仅儿童健康部就使用了科勒布国家输血服务中心处理的全部血液的32.2%,但在新生儿期之后的儿童中,每年急诊室554例死亡病例中多达259例(58.1%)与重度贫血有关。缺铁是贫血最常见的原因,也是镰状细胞病和蛋白质-能量营养不良性贫血的进一步病因。鉴于在发达国家,通过改善营养咨询、食品铁强化以及对婴儿和学童进行铁补充,儿童贫血患病率显著下降,且有记录表明随之而来的生长速度和智力表现有所改善,我们支持计划中的全国贫血调查,并建议尽早考虑对有风险的大龄婴儿和学龄前儿童进行铁补充。