1 The Danish Knowledge Centre for Rehabilitation and Palliative Care (REHPA), Odense University Hospital and University of Southern Denmark, Denmark.
2 National Institute of Public Health, University of Southern Denmark, Denmark.
Eur J Prev Cardiol. 2018 Jan;25(2):142-149. doi: 10.1177/2047487317733074. Epub 2017 Sep 27.
Background Patient-reported health-related quality of life is increasingly used as an outcome measure in clinical trials and as a performance measure to evaluate quality of care. The objective of this study was to assess the psychometric properties of the Danish HeartQoL questionnaire, a core heart disease-specific health-related quality of life questionnaire, in implantable cardioverter defibrillator recipients. Design This study involved cross-sectional and test-retest study designs. Method Implantable cardioverter defibrillator recipients in the cross-sectional study completed the HeartQoL, the Short-Form 36 Health Survey, and the Hospital Anxiety and Depression Scale. The HeartQoL structure, construct-related validity (convergent and discriminative) and reliability (internal consistency) were assessed. HeartQoL reproducibility (test-retest) was assessed in an independent sample of implantable cardioverter defibrillator recipients. Results Mokken scale analysis supported the bi-dimensional structure of HeartQoL among 358 implantable cardioverter defibrillator recipients. Convergent ( r > 0.72) and discriminative validity were confirmed. The HeartQoL scales demonstrated satisfactory internal consistency (Cronbach's alpha > 0.90). Test-retest reliability (two weeks interval) was assessed in 89 implantable cardioverter defibrillator recipients and found to be acceptable for each scale (intra-class correlation > 0.90). Conclusion The Danish HeartQoL questionnaire demonstrated satisfactory key psychometric attributes of validity and reliability in this implantable cardioverter defibrillator population. This study adds support for the HeartQoL as a core heart-specific health-related quality of life questionnaire in a broad group of patients with heart disease including implantable cardioverter defibrillator recipients.
患者报告的健康相关生活质量越来越多地被用作临床试验的结果衡量标准和评估护理质量的绩效衡量标准。本研究的目的是评估丹麦 HeartQoL 问卷（一种核心心脏病特异性健康相关生活质量问卷）在植入式心脏复律除颤器（ICD）受者中的心理测量特性。
本研究包括横断面研究和重测研究设计。
横断面研究中的 ICD 受者完成了 HeartQoL、简短健康调查 36 项量表和医院焦虑抑郁量表。评估了 HeartQoL 的结构、与结构相关的有效性（收敛和判别）和可靠性（内部一致性）。在独立的 ICD 受者样本中评估了 HeartQoL 的可重复性（重测）。
Mokken 量表分析支持 358 名 ICD 受者的 HeartQoL 具有二维结构。验证了收敛（r＞0.72）和判别有效性。HeartQoL 量表显示出令人满意的内部一致性（Cronbach's alpha＞0.90）。在 89 名 ICD 受者中评估了重测可靠性（两周间隔），发现每个量表的可靠性都可以接受（组内相关系数＞0.90）。
丹麦 HeartQoL 问卷在 ICD 人群中表现出令人满意的有效性和可靠性的关键心理测量特性。这项研究为 HeartQoL 作为一种广泛的心脏病患者（包括 ICD 受者）的核心心脏特异性健康相关生活质量问卷提供了支持。
