测量缺血性心脏病患者报告的结局：希腊心脏生活质量问卷的验证
Measuring Patient-Reported Outcomes in Ischemic Heart Disease: Validation of the Greek HeartQoL Questionnaire.
作者信息
Dimitriadou Ioanna, Deaton Christi, Fradelos Evangelos C, Skoularigis John, Vogiatzis Ioannis, Sdogkos Evangelos, Toska Aikaterini, Tsiara Eleni, Christakis Anastasios, Anagnostopoulou Dimitra, Saridi Maria
机构信息
Department of Nursing, Laboratory of Clinical Nursing, University of Thessaly, Larissa, Greece.
Department of Public Health and Primary Care, University of Cambridge School of Clinical Medicine, Cambridge, UK.
出版信息
Am J Med Open. 2025 Mar 20;14:100098. doi: 10.1016/j.ajmo.2025.100098. eCollection 2025 Dec.
BACKGROUND
The Greek HeartQoL questionnaire is designed to assess health-related quality of life (HRQoL) in patients with ischemic heart disease.
OBJECTIVES
This study aims to validate its psychometric properties in Greek patients diagnosed with angina pectoris, myocardial infarction, and ischemic heart failure.
METHODS
A cross-sectional study was conducted with 158 patients from five clinical sites in Greece. Participants completed the Greek HeartQoL, the Short Form-36 Health Survey, and the Hospital Anxiety and Depression Scale. Psychometric evaluations included Mokken scale analysis, reliability testing with Cronbach's alpha, and validity assessments through Spearman correlation coefficients, and analysis of covariance.
RESULTS
The Greek HeartQoL exhibited excellent internal consistency, with Cronbach's alpha values exceeding 0.90. Factor analysis confirmed the questionnaire's two-factor structure, effectively capturing physical and emotional dimensions of HRQoL. Convergent validity was demonstrated by strong correlations with Short Form-36 Health Survey ( > 0.70), and discriminative validity was confirmed by significant differences in HRQoL scores between patients with angina pectoris, myocardial infarction, and ischemic heart failure ( < .001).
CONCLUSIONS
The findings suggest that the Greek HeartQoL demonstrates strong reliability and validity in assessing HRQoL in Greek ischemic heart disease patients. However, further studies with larger and more diverse samples are needed to confirm its psychometric properties across different clinical populations.
背景
希腊心脏生活质量问卷旨在评估缺血性心脏病患者的健康相关生活质量（HRQoL）。
目的
本研究旨在验证其在诊断为心绞痛、心肌梗死和缺血性心力衰竭的希腊患者中的心理测量特性。
方法
对来自希腊五个临床地点的158名患者进行了横断面研究。参与者完成了希腊心脏生活质量问卷、简短健康调查36项量表（Short Form-36 Health Survey）和医院焦虑抑郁量表。心理测量评估包括莫肯量表分析、使用克朗巴赫α系数进行可靠性测试，以及通过斯皮尔曼相关系数和协方差分析进行效度评估。
结果
希腊心脏生活质量问卷表现出出色的内部一致性，克朗巴赫α系数值超过0.90。因子分析证实了该问卷的两因素结构，有效地捕捉了健康相关生活质量的身体和情感维度。与简短健康调查36项量表的强相关性（>0.70）证明了收敛效度，心绞痛、心肌梗死和缺血性心力衰竭患者之间健康相关生活质量得分的显著差异（<.001）证实了区分效度。
结论
研究结果表明，希腊心脏生活质量问卷在评估希腊缺血性心脏病患者的健康相关生活质量方面具有很强的可靠性和效度。然而，需要进一步对更大、更多样化的样本进行研究，以确认其在不同临床人群中的心理测量特性。
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